Results 51 to 60 of about 240,144 (264)

Model sensitivity limits attribution of greenhouse gas emissions to polar bear demographic rates

open access: yesScientific Reports
Greenhouse gas emissions continue to increase and negatively affect sea ice conditions that polar bears rely on. It is therefore important to better understand how specific emissions levels affect polar bear demography.
Ryan R. Wilson, Erik M. Andersen
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Characteristic of complete mitochondrial genome and phylogenetic status of a muskrat, Ondatra zibethicus (Rodentia: Cricetidae) in South Korea

open access: yesMitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of Muskrat, Ondatra zibethicus (Rodentia: Cricetidae) in Korea was sequenced for the first time using the next-generation sequencing method to understand its evolutionary relationship and to be helpful to establish a ...
Young-Chae Kim   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Conserving Mammals

open access: yes, 2021
The overall global pattern of mammal diversity is similar to other taxonomic groups such as birds and amphibians, being the Andes mountain range and the Amazonas in South-America, sub-Saharan Africa and Southeast Asia among the regions with greatest number of species.
Cuadros-Casanova Ivon, Rondinini Carlo
openaire   +2 more sources

Do marine mammals diversify more slowly than non‐marine mammals? [PDF]

open access: yes
Aim Species richness is generally lower in marine than in terrestrial ecosystems, but the reasons behind this disparity remain unclear. This study examines whether marine mammals diversify at a slower pace than their non‐marine counterparts, aiming to ...
Gamboa Jurado-Centurion, Sara   +21 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Herpesvirus Infection in a Breeding Population of Two Coexisting Strix Owls

open access: yesAnimals, 2021
Birds are a frequent host of a large variety of herpesviruses, and infections in them may go unnoticed or may result in fatal disease. In wild breeding populations of owls, there is very limited information about the presence, impact, and potential ...
Zoran Žlabravec   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Capture and Release of Minke Whales Offers New Research Opportunities, Including Measurements of Mysticete Hearing [PDF]

open access: yes
Knowledge about species-specific hearing is vital to assessing how anthropogenic noise impacts marine mammals. Unfortunately, no empirical audiogram exists for any mysticete whale.
Teilmann, Jonas   +7 more
core   +1 more source

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