Results 51 to 60 of about 1,142,661 (285)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Herpesvirus Infection in a Breeding Population of Two Coexisting Strix Owls

open access: yesAnimals, 2021
Birds are a frequent host of a large variety of herpesviruses, and infections in them may go unnoticed or may result in fatal disease. In wild breeding populations of owls, there is very limited information about the presence, impact, and potential ...
Zoran Žlabravec   +5 more
doaj   +1 more source

Antarctic marine mammals and ocean acoustics [PDF]

open access: yes, 2006
Marine mammals rely on sound and hearing as their primary means of communication and sensing their world. Concerns that anthropogenic sound in the ocean could infer their sensing, cause stress or even damage their hearing physically rose a controversial ...
Boebel, Olaf   +5 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Characteristic of complete mitochondrial genome and phylogenetic status of a muskrat, Ondatra zibethicus (Rodentia: Cricetidae) in South Korea

open access: yesMitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of Muskrat, Ondatra zibethicus (Rodentia: Cricetidae) in Korea was sequenced for the first time using the next-generation sequencing method to understand its evolutionary relationship and to be helpful to establish a ...
Young-Chae Kim   +7 more
doaj   +1 more source

Lice, Mites, and Ticks of Southeastern Wisconsin Mammals [PDF]

open access: yes, 2017
Seventeen species of southeastern Wisconsin mammals were found to 6e infected with arthropod ectoparasites other than fleas. One host species was infested with one species of biting lice (Mallophaga), five with five species of sucking lice (Anoplura ...
Amin, Omar M
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Human streptococcus agalactiae strains in aquatic mammals and fish [PDF]

open access: yes, 2013
<p>Background: In humans, Streptococcus agalactiae or group B streptococcus (GBS) is a frequent coloniser of the rectovaginal tract, a major cause of neonatal infectious disease and an emerging cause of disease in non-pregnant adults.
Crumlish, M.   +7 more
core   +5 more sources

Mammals

open access: yesKoedoe, 1988
At last! A book that tells visitors to the Kruger National Park much more than just gestation period and record horn length of the larger mammals.
openaire   +3 more sources

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