Results 71 to 80 of about 1,142,661 (285)
Organic farms as refuges for small mammal biodiversity in agro ecosystems [PDF]
, 2011 Habitat fragmentation, the process by which relatively continuous habitats is broken into smaller pieces, occurs in natural systems but is to a high degree also human-induced through landscape use.
Hansen, Tine Sussi +2 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Journal of Ethnobiology and Ethnomedicine, 2019 Background Paha hunting is a commonplace recreational activity in the mountainous regions of Nepal. The collection is primarily for food use and secondarily preferred as medicinal forms, and utilized by many ethnic groups: Magar, Rai, Gurung, Jirel, etc.
Biraj Shrestha, Min Bahadur Gurung
doaj +1 more source
The accelerating influence of humans on mammalian macroecological patterns over the late Quaternary [PDF]
, 2019 The transition of hominins to a largely meat-based diet ~1.8 million years ago led to the exploitation of other mammals for food and resources. As hominins, particularly archaic and modern humans, became increasingly abundant and dispersed across the ...
Elliott Smith, Rosemary E. +4 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Tidal and seasonal influences in dolphin habitat use in a southern Brazilian estuary
Scientia Marina, 2017 In this study we describe how franciscana and Guiana dolphin habitat use is influenced by tidal cycles and seasonality in Babitonga Bay. The franciscanas use a greater area in winter and a smaller area in summer, but the extent of the area used did not ...
Renan Lopes Paitach +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Rescue, rehabilitation, and release of marine mammals: An analysis of current views and practices. [PDF]
, 1996 Stranded marine mammals have long attracted public attention. Those that wash up dead are, for all their value to science, seldom seen by the public as more than curiosities.
Geraci, Joseph R. +2 more
core
Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion [PDF]
, 2009 Two dynamin-related protein (DRP) families are essential for fusion of the outer and inner mitochondrial membranes, Fzo1 (yeast)/Mfn1/Mfn2 (mammals) and Mgm1 (yeast)/Opa1 (mammals), respectively.
Rachel M. DeVay +50 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source