Results 61 to 70 of about 31,467 (302)

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Efficacy of Vitex pseudo-negundo in a Bovine Mastitis Model Experimentally Induced by Staphylococcus aureus in Rats. [PDF]

Vet Med Sci
This study evaluated the therapeutic efficacy of Vitex pseudo‐negundo (VPN) extracts in a Staphylococcus aureus‐induced mastitis rat model. Following extraction with water, methanol and petroleum ether, in vitro MICs were determined. Rats established with mastitis received 5‐day treatments.
Koç H, Fındık A, Güvenç T, Batan N, Fandaklı S, Fındık M.   +5 more
europepmc   +2 more sources

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

Comparative Histological Study on Mammary Gland of Domestic Animals

Journal of Advances in Biology & Biotechnology
The present study was conducted on mammary gland of domestic animals to study and compare the histoarchitecture of mammary glands of different domestic animals. The tissue samples of mammary gland of 6 adult buffalo, 6 cattle, 15 sheep, 15 goats, 6 dogs and 6 pigs were collected.
Urmila, T. Sai, Ramayya, P. Jagapathi, Lakshmi, M. Santhi, Kumar, R.V. Suresh, Amaravathi, P   +4 more
openaire   +2 more sources

Paternal malnutrition programs breast cancer risk and tumor metabolism in offspring

Breast Cancer Research, 2018
Background While many studies have shown that maternal factors in pregnancy affect the cancer risk for offspring, few studies have investigated the impact of paternal exposures on their progeny’s risk of this disease.
Raquel Santana da Cruz, Elissa J. Carney, Johan Clarke, Hong Cao, M. Idalia Cruz, Carlos Benitez, Lu Jin, Yi Fu, Zuolin Cheng, Yue Wang, Sonia de Assis   +10 more
doaj   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Mammary glands, aquaporins and milk production

, 2020
The mammary gland is a specialized, enlarged sudoriferous or sweat (apocrine) gland that produces and secretes milk during lactation. Milk consists of simple sugars, lipids, proteins, vitamins and minerals dissolved in water, which accounts for up to 88%
Mobasheri, A
core   +1 more source

Dominant negative retinoic acid receptor initiates tumor formation in mice

Molecular Cancer, 2006
Background Retinoic acid suppresses cell growth and promotes cell differentiation, and pharmacological retinoic acid receptor (RAR) activation is anti-tumorigenic.
Farias Eduardo F, Marzan Christine, Cattoretti Giorgio, Kupumbati Tara S, Taneja Reshma, Mira-y-Lopez Rafael   +5 more
doaj   +1 more source

Expression profile of caseins, estrogen and prolactin receptors in mammary glands of dairy ewes [PDF]

, 2010
In this study, we analyzed the developmental expression of estrogen receptors (ESR1 and ESR2), prolactin receptors (PRLR) and casein genes (CSN1S1, CSN1S2, CSN2 and CSN3) in the ewe mammary glands from prepubertal stage to involution. Using Real-time PCR
Giuseppe Pulina, Pulina, G., PULINA G., Monica Colitti, Colitti, Monica, Pulina, Giuseppe   +5 more
core   +1 more source

Effect of Maternal Gradient Nutritional Restriction during Pregnancy on Mammary Gland Development in Offspring

, 2023
We aimed to investigate the effect of different levels of nutritional restriction on mammary gland development during the embryonic period by gradient nutritional restriction in pregnant female mice. We started the nutritional restriction of 60 female CD-
Zhiyong Hu, Qiuling Hou, Yun Wang, Xusheng Dong, Zhonghua Wang, Xueyan Lin   +5 more
core   +1 more source