Results 51 to 60 of about 31,467 (302)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Mammary Glands of Women, Female Dogs and Female Rats: Similarities and Differences to Be Considered in Breast Cancer Research

open access: yesVeterinary Sciences, 2023
Breast cancer is one of the most common and well-known types of cancer among women worldwide and is the most frequent neoplasm in intact female dogs. Female dogs are considered attractive models or studying spontaneous breast cancer, whereas female rats ...
Tiago Ferreira   +8 more
doaj   +1 more source

Genetic and clinical studies of teat traits in the pig [PDF]

open access: yes, 2013
A major goal of pig breeding is to produce sows with good longevity, which can raise many uniform litters with healthy, fast-growing piglets. The fitness of the sow, including the presence of sufficient number of functional teats, is one key to the ...
Chalkias, Helena
core  

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou   +12 more
wiley   +1 more source

Mammary epithelial cells isolated from milk are a valuable, non-invasive source of mammary transcripts

open access: yesFrontiers in Genetics, 2015
Milk is produced in the udder by mammary epithelial cells (MEC). Milk contains MEC, which are gradually exfoliated from the epithelium during lactation.
Marion eBoutinaud   +6 more
doaj   +1 more source

Occurrence and reasons for on-farm emergency slaughter of cattle in Norway

open access: yesFrontiers in Veterinary Science, 2022
On-farm emergency slaughter (OFES) accounts for more than 4% of all cattle slaughter in Norway. The practice raises questions about animal welfare, public health, and the sustainability of cattle production.
Gíslína Skúladóttir   +4 more
doaj   +1 more source

Ultrasonographic assessment of the feline mammary gland.

open access: yes, 2008
The aim of this study is to characterise the feline mammary echotexture using B-mode ultrasonography, which is not routinely used to examine the feline mammary gland. Using a 5-9 MHz linear transducer the ultrasonographic appearance of non-stimulated and
Payan-Carreira, R., Bessa, Ana Martins
core   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian   +7 more
wiley   +1 more source

Effect of Falcaria Vulgaris on Milk Production Parameters in Female Rats’ Mammary Glands

open access: yesJournal of Family and Reproductive Health, 2019
Objective: Falcaria Vulgaris (F.Vulgaris) is a multipurpose herb in traditional medicine, containing essential amino acids, vitamins and numerous nutrients.
Mohammad Reza Salahshoor   +3 more
doaj  

Hemangiopericytoma in a female dog with direct invasion of abdominal cavity and pulmonary metastasis

open access: yesCiência Rural, 2014
An intact adult female Poodle dog was presented with a history of an increase in volume in the left and right mammary inguinal glands. The histopathological examination revealed a proliferation of spindle cells arranged in bundles with concentric ...
Elisângela Olegário da Silva   +4 more
doaj   +1 more source

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