Results 201 to 210 of about 42,440 (264)

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Spatial localization of avian and human influenza A virus receptors in male and female bovine reproductive tissues. [PDF]

Sci Rep
Poliakiwski BD, Minela T, Smith DJ, Seekford ZK, Cain JW, Polanco O, Johnson GA, Luense LJ, Ross PJ, Dimitrov KM, Lamb GC, Pohler KG.   +11 more
europepmc   +1 more source

Small Extracellular Vesicle‐Derived Nidogen 1 Promotes HCC Carcinogenesis via Transglutaminase 3‐Mediated YAP/TAZ Signalling

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
NID1‐rich sEVs released by HCC cells are internalized by recipient cells, where the C‐terminal region of NID1 binds to and stabilizes TGM3. This activates integrin‐FAK/Src/AKT and Hippo‐YAP/TAZ signalling, thereby promoting HCC proliferation, colony formation, migration, invasion, tumour growth, and lung metastasis.
Cherlie Lot Sum Yeung, Le Cui, Jingyi Wang, Ching‐Ping Chan, Tung Him Ng, Charlotte Jiaqi Lai, Xiaowen Mao, Sze Keong Tey, Michael Shing Yan Huen, Judy Wai Ping Yam   +9 more
wiley   +1 more source

Late gestational exposure to flutamide alters stromal composition and immune landscape in the rat mammary gland during pre-puberty, peri-puberty, and adulthood. [PDF]

Toxicol Sci
Tovar Parra D, McDermott A, Cardot J, Juarez MN, Joao F, El Omri-Charai R, Berthiaume L, Dhawan B, Aghigh A, Breton Y, Légaré F, Delbès G, Pelletier M, Audet-Walsh É, Plante I.   +14 more
europepmc   +1 more source

Multi-omics profiling uncovers immune-molecular clusters with distinct chemo-immunotherapeutic vulnerabilities in a mouse model of triple-negative breast cancer. [PDF]

Mol Cancer
Castellanet O, Monatte J, Corvaisier N, Kaoutari AE, Kaya M, Ferreira L, Audebert S, Camoin L, de Nonneville A, Gonçalves A, Borg JP, Michea P, Maina F, Lamballe F.   +13 more
europepmc   +1 more source

Luminal hormone-responsive cells tune the regenerative remodeling of mammary glands in large mammals. [PDF]

Cell Discov
Li Y, Zhang L, Luo T, Zhang W, Wang T, Liu F, Lin S, Luo J, Liu J, Peng J, Wang C, Wang W, Shi H.   +12 more
europepmc   +1 more source

Compressive stress-driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory. [PDF]

Sci Adv
Boyle ST, Gallego-Ortega D, Buckley EJ, Cognard E, Johan MZ, Esmaeili Z, Kamei M, Poole K, Samuel MS.   +8 more
europepmc   +1 more source

Elucidating cooperative genetic events in DCIS progression in mutant <i>p53</i>-driven breast cancer. [PDF]

Proc Natl Acad Sci U S A
Morrissey RL, McDaniel JM, Chau GP, Su X, V M, Chandra V, Dixon BREA, El-Naggar AK, Thompson AM, Lozano G.   +9 more
europepmc   +1 more source

An in utero exposure to the synthetic estrogen diethylstilbestrol affects the fat pad composition in post-natal mammary glands. [PDF]

Toxicol Sci
Tovar-Parra D, McDermott A, Cardot J, Juarez MN, Joao F, El Omri-Charai R, Berthiaume L, Dhawan B, Aghigh A, Breton Y, Légaré F, Delbès G, Pelletier M, Audet-Walsh É, Plante I.   +14 more
europepmc   +1 more source

Expression of histamine in tumours of human mammary gland

Journal of Physiology and Pharmacology, 1997
Maślińska, D, Wagner, T, Górnicka, M
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