Results 181 to 190 of about 42,336 (264)

Uterine adenocarcinoma with peritoneal carcinomatosis in a cat: HBME-1 as a potential marker for uterine epithelial disorders in queens. [PDF]

Vet Res Commun
Hartmann G, Lamego ÉC, Paz MC, Bandinelli MB, Pavarini SP.   +4 more
europepmc   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, Volume 13, Issue 33, 15 June 2026.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Pleiotrophin in Mammary Gland Development and Breast Cancer: A Comprehensive Review of the Evidence. [PDF]

Cells
Gholami AS, Walsh CN, McBryan J.
europepmc   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis. [PDF]

Science
Collado-Sole A, Borjini N, Zhai J, Ruiz-Pino F, Soria-Alcaide G, Folgueira C, García-Vilela C, Romero-de la Rosa B, Lopez V, Zouaghi Y, Jacobs A, Mora-Romero B, Barranco A, Yoldi G, Rizzoti K, Sabio G, Perez-Chacon G, Santamaria PG, Esteban JA, Journiac N, Prevot V, Pascual A, Fernández-Chacón R, Tena-Sempere M, Pitteloud N, Gonzalez-Suarez E.   +25 more
europepmc   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

Advanced Science, Volume 13, Issue 32, 9 June 2026.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz, Riley J. Deutsch‐Williams, Ralph Weissleder   +2 more
wiley   +1 more source

Primary Apocrine Adenocarcinoma of the Vulva: A Report of a Rare Case. [PDF]

Cureus
Yoakam M, Friday J, Weitoschova A, Borger K, Windsor D, Dunbar B, Shirley V.   +6 more
europepmc   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Comparative Transcriptomics Suggests that Breast Secretory Epithelium Reuses Gene Repertoires Conserved Across Vertebrates Beyond Mammals. [PDF]

Genome Biol Evol
Saitou M.
europepmc   +1 more source