Results 21 to 30 of about 43,371 (303)

Cutaneous eccrine glands of the foot pads of the rock hyrax (Procavia capensis, Hyracoidea, mammalia) [PDF]

, 2002
In order to find correlations between skin gland morphology and specific ethological features, the cutaneous glands of the foot pads of Procavia capensis were studied by histological and various histochemical methods and by electron microscopy.
Stumpf, P., Welsch, U.
core   +1 more source

Physiological roles of the oncoprotein c-Myc in mouse mammary gland development [PDF]

, 2009
c-Myc, a transcription factor that affects a large number of target genes, is one of the most frequently deregulated oncoproteins in human cancer. The wide-ranging biological functions of c-Myc include regulation of the cell cycle, differentiation ...
Stölzle, Tina
core   +1 more source

A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture

Biology Open, 2020
Mouse mammary organ culture (MMOC) is used to evaluate the efficacy of chemopreventive agents against the development of carcinogen-induced preneoplastic lesions and is highly correlative to in vivo carcinogenesis models. Here, we developed a new ex vivo
Akash Gupta, Geetanjali Gupta, Rajeshwari R. Mehta, David Z. Ivancic, Rashidra R. Walker, Jankiben R. Patel, Karen M. Gallegos, A. Michael Davidson, Seema A. Khan, Rajendra G. Mehta, Syreeta L. Tilghman   +10 more
doaj   +1 more source

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]

, 2005
We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J, Whitelaw C. B. A., ACCORSI, PIER ATTILIO, Hurley, W, Boutinaud, M, Kolb A., Allan G. A., Tonner, E, Wilde, C J, Boutinaud M., Wilde C. J., Beattie J., Accorsi, P A, Flint, D J, Flint D. J., Tonner E., Whitelaw, C B A, Hurley W., Kolb, A F, Allan, G J   +19 more
core   +1 more source

Pea3 transcription factors and wnt1-induced mouse mammary neoplasia.

PLoS ONE, 2010
The role of the PEA3 subfamily of Ets transcription factors in breast neoplasia is controversial. Although overexpression of PEA3 (E1AF/ETV4), and of the related factors ERM (ETV5) and ER81 (ETV1), have been observed in human and mouse breast tumors ...
Rebecca Baker, Claire V Kent, Rachel A Silbermann, John A Hassell, Lawrence J T Young, Louise R Howe   +5 more
doaj   +1 more source

Cellular and molecular effects of early pregnancy on mammary epithelial cell subpopulations in mice and their potential relevance for breast cancer protection [PDF]

, 2013
The breast cancer protective effect of an early pregnancy is well established in both humans and rodents, but the underlying mechanism is unclear. Since breast cancers are thought to originate from distinct mammary epithelial cell subtypes, we studied ...
Meier-Abt, Fabienne
core   +1 more source

Fry Is Required for Mammary Gland Development During Pregnant Periods and Affects the Morphology and Growth of Breast Cancer Cells

Frontiers in Oncology, 2019
The Fry gene, located on chromosome 13, is an evolutionarily conserved large protein from yeast to human. Our previous study genetically linked the Fry gene with differential susceptibility to mammary carcinogenesis, but whether Fry affects mammary gland
Yan Liu, Yan Liu, Xushen Chen, Zhihong Gong, Zhihong Gong, Hao Zhang, Fan Fei, Xiaojiang Tang, Jie Wang, Peilin Xu, Helmut Zarbl, Xuefeng Ren   +11 more
doaj   +1 more source

Analysis of in vivo functions of Memo in embryonic and mammary gland development [PDF]

, 2007
Studies from our lab recently led to the discovery of Memo (mediator of ErbB2-driven cell motility), a novel 297 amino acid protein shown to be required for ErbB2- and other receptor tyrosine kinase-driven cell motility in breast tumor cells.
Kaeser, Patrick
core   +1 more source

Evaluation of Cytokeratin 7 Expression in Different Mammary Gland Neoplasms [PDF]

Iranian Journal of Veterinary Medicine, 2021
BACKGROUND: Cytokeratins are non-contractile intermediate filaments engaged in anchoring and structural functions forming a network to support cytoplasm.
Elnaz Elahirad, Farhang Sasani, Alireza Khosravi, Mohammad Javad Gharagozlou, Fateme Khanbarari   +4 more
doaj   +1 more source

Label-free isolation and cultivation of patient-matched human mammary epithelial and stromal cells from normal breast tissue

European Journal of Cell Biology, 2021
Breast cancer is primarily derived from mammary epithelial cells, the main cell type in human mammary glands. The majority of knowledge gained thus far around breast cancer has come from research using immortalized epithelial cell lines.
Maria K. Koch, Berline Murekatete, Dietmar W. Hutmacher, Larisa M. Haupt, Laura J. Bray   +4 more
doaj   +1 more source