Results 31 to 40 of about 42,440 (264)
Reprogramming Human Cancer Cells in the Mouse Mammary Gland [PDF]
Cancer Research, 2010 Abstract The tissue microenvironment directs stem/progenitor cell behavior. Cancer cells are also influenced by the microenvironment. It has been shown that, when placed into blastocysts, cancer cells respond to embryonic cues and differentiate according to the tissue type encountered during ontological development.
Karen M, Bussard +4 more
openaire +2 more sources
Diagnostic Pathology, 2010 A rare case of an apocrine tumor in the male perineal region is reported. A dermal cystic lesion developed in the region between the anus and scrotum of a 74-year-old Japanese male. The cystic lesion, measuring 3.5 × 5.0 cm in size, was lined by columnar
Yoshioka Takako +4 more
doaj +1 more source
Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer
Neoplasia: An International Journal for Oncology Research, 2017 Claudin-low breast cancer (CLBC) is a poor prognosis molecular subtype showing stemness and mesenchymal features. We previously discovered that deletion of a Notch signaling modulator, Lunatic Fringe (Lfng), in the mouse mammary gland induced a subset of
Wen-Cheng Chung +4 more
doaj +1 more source
Milk Proteins Are Predigested Within the Human Mammary Gland [PDF]
Journal of Mammary Gland Biology and Neoplasia, 2017 Previous work demonstrates that proteases present in human milk release hundreds of peptides derived from milk proteins. However, the question of whether human milk protein digestion begins within the mammary gland remains incompletely answered. The primary objective of this study was to determine whether proteolytic degradation of human milk proteins ...
Søren D. Nielsen +2 more
openaire +2 more sources
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Radiological features of breast benign lesions in patients with hyperprolactinemia [PDF]
Archive of Oncology, 2007 Background: The study was conducted to determine whether prolactin (PRL) influences radiological features of benign breast lesions. Methods: During the 4-year period, we observed 50 patients with nipple discharge: 23 with normal serum prolactin levels ...
Radojković Danijela +5 more
doaj +1 more source
An Insight into Probiotics Bio-Route: Translocation from the Mother’s Gut to the Mammary Gland
Applied Sciences, 2021 Human breast milk (HBM) is unique in its composition as it is adapted to fulfil the newborns’ nutritional requirement and helps in improving the health of newborns. Besides various nutrients, the human milk also contains diverse group of microbiotas. The
Shanmugaprakasham Selvamani +12 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Geometry‐driven design of soft cellular metamaterials is systematically investigated by combining experiments, finite element modeling, and statistical prediction. The study quantifies how unit cell geometry and material properties govern stiffness, instability, densification, and energy absorption.
Alice Berardo +4 more
wiley +1 more source