Results 31 to 40 of about 43,371 (303)

Immunohistochemical Expression of p62 in Feline Mammary Carcinoma and Non-Neoplastic Mammary Tissue

Animals, 2022
The p62 protein, also called sequestosome 1 (SQSTM1), is a ubiquitin-binding scaffold protein. In human oncology, although the interest in the function of this protein is recent, the knowledge is now numerous, but its role in tumorigenesis is not yet ...
Gian Enrico Magi, Francesca Mariotti, Lorenzo Pallotta, Alessandro Di Cerbo, Franco Maria Venanzi   +4 more
doaj   +1 more source

Precursors of hexoneogenesis within the human mammary gland

American Journal of Physiology-Endocrinology and Metabolism, 2015
The human mammary gland is capable of de novo synthesis of glucose and galactose (hexoneogenesis); however, the carbon source is incompletely understood. In this study, we investigated the role of acetate, glutamine, lactate and glycerol as potential carbon sources for hexoneogenesis.
Mahmoud A, Mohammad, Patricia, Maningat, Agneta L, Sunehag, Morey W, Haymond   +3 more
openaire   +3 more sources

Pathological and genetic aspects of spontaneous mammary gland tumor in Tupaia belangeri (tree shrew).

PLoS ONE, 2020
Mammary gland cancer is the most common cancer occurring in women globally. Incidences of this cancer in Japan are on the increase. Annually, more than 70,000 new cases are recorded in Japan and about 1.7 million in the world.
Chi Hai-Ying, Yuki Tanaka, Tatsuro Hifumi, Koichiro Shoji, Mohammad Enamul Hoque Kayesh, Md Abul Hashem, Bouchra Kitab, Takahiro Sanada, Tomoko Fujiyuki, Misako Yoneda, Hitoshi Hatai, Akira Yabuki, Noriaki Miyoshi, Chieko Kai, Michinori Kohara, Kyoko Tsukiyama-Kohara   +15 more
doaj   +1 more source

β-Defensin Expression in Human Mammary Gland Epithelia [PDF]

Pediatric Research, 2000
Milk of mammalian species contains a wide spectrum of anti-infectious factors, some of which are heat stable. Focusing on recently discovered heat-stable antibacterial peptides called defensins, which are expressed in epithelial tissues such as airway, skin, and kidney, we hypothesized that mammary gland epithelia produce and secrete defensins onto the
C R, Tunzi, P A, Harper, B, Bar-Oz, E V, Valore, J L, Semple, J, Watson-MacDonell, T, Ganz, S, Ito   +7 more
openaire   +2 more sources

Id-1 is not expressed in the luminal epithelial cells of mammary glands [PDF]

, 2003
BackgroundThe family of inhibitor of differentiation/DNA binding (Id) proteins is known to regulate development in several tissues. One member of this gene family, Id-1, has been implicated in mammary development and carcinogenesis.
Galvez, Jose J, Jose J Galvez, Benezra, Robert, Shyamala, Gopalan, Cardiff, Robert D, Uehara, Norihisa, Gopalan Shyamala, Yu-Chien Chou, Paola de-Candia, Robert D Cardiff, Norihisa Uehara, Robert Benezra, Chou, Yu-Chien, de-Candia, Paola   +13 more
core   +2 more sources

Over-expression of mammaglobin-B in canine mammary tumors

BMC Veterinary Research, 2018
Background Mammaglobin, a member of secretoglobin family has been recognized as a breast cancer associated protein. Though the exact function of the protein is not fully known, its expression has been reported to be upregulated in human breast cancer.We ...
Mamta Pandey, B. V. Sunil Kumar, Kuldip Gupta, Ram Saran Sethi, Ashwani Kumar, Ramneek Verma   +5 more
doaj   +1 more source

Co-administering Melatonin With an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mammary Cancer Development in a Mouse Model of HER2-Positive Breast Cancer

Frontiers in Oncology, 2019
Melatonin has numerous anti-cancer properties reported to influence cancer initiation, promotion, and metastasis. With the need for effective hormone therapies (HT) to treat menopausal symptoms without increasing breast cancer risk, co-administration of ...
Balasunder R. Dodda, Corry D. Bondi, Mahmud Hasan, William P. Clafshenkel, Katie M. Gallagher, Mary P. Kotlarczyk, Shalini Sethi, Ethan Buszko, Jean J. Latimer, J. Mark Cline, Paula A. Witt-Enderby, Paula A. Witt-Enderby, Vicki L. Davis   +12 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Human milk protein production in xenografts of genetically engineered bovine mammary epithelial stem cells. [PDF]

PLoS ONE, 2010
BACKGROUND: In the bovine species milk production is well known to correlate with mammary tissue mass. However, most advances in optimizing milk production relied on improvements of breeding and husbandry practices.
Eugenio Martignani, Peter Eirew, Paolo Accornero, Connie J Eaves, Mario Baratta   +4 more
doaj   +1 more source

Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation [PDF]

, 2008
Introduction The prolactin-Janus-kinase-2-signal transducer and activator of transcription-5 (JAK2-STAT5) pathway is essential for the development and functional differentiation of the mammary gland.
Liu, R., Bork, Peer, Shemanko, Carrie S., Shemanko, C., Liu, Ruixuan, Pfitzner, Edith, Schultz, J., Christine T Parusel, Jörg Schultz, Groner, Bernd, Parusel, Christine T., Bork, P., Boecher, N., Perotti, Christian, Christian Perotti, Ruixuan Liu, Carrie S Shemanko, Pfitzner, E., Groner, B., Schultz, Jörg, Bernd Groner, Böcher, Nadine, Nadine Böcher, Perotti, C., Peer Bork, Edith Pfitzner, Parusel, C.   +26 more
core   +1 more source