Results 1 to 10 of about 190,981 (166)
Comparison of the Expression of Acetylated Histones H3 and H4 and the Deacetylase Enzymes HDACs 1, 2, and 6 in Neoplastic and Nonneoplastic Canine Mammary Tissues. [PDF]
Vet Med IntEpigenetic alterations play a crucial role in the pathogenesis of cancer, as changes in the expression of DNA-associated proteins can affect gene expression. However, these changes may be reversible following treatment.
Senhorello ILS +10 more
europepmc +2 more sources
Macroscopic changes in the mammary glands of healthy cats after progestogen administration
Semina: Ciências Agrárias, 2023 The administration of contraceptives in female cats leads to problems such as pyometra, fetal maceration, mammary hyperplasia, and mammary neoplasms.
Maisa Martins Quirilos Assis +7 more
doaj +1 more source
Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females.
Frontiers in Nutrition, 2016 Obesity is a worldwide epidemic, and the comorbidities associated with obesity are numerous. Over the last two decades, we and others have employed an outbred rat model to study the development and persistence of obesity, as well as the metabolic ...
Erin D Giles +2 more
doaj +1 more source
Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
Cell Reports, 2018 Summary: Janus kinases (JAKs) and their downstream STAT proteins play key roles in cytokine signaling, tissue homeostasis, and cancer development. Using a breast cancer model that conditionally lacks Janus kinase 1, we show here that JAK1 is essential ...
Barbara L. Wehde +5 more
doaj +1 more source
Sonodynamic and sono-photodynamic therapy in oncology
Biomedical Photonics, 2019 In the present publication, authors have analyzed the results of using sonodynamic and sono-photodynamic therapy with photosensitizing agents of various classes (hematoporphyrin, 5-aminolevulinic acid, chlorin derivatives, etc.) in experimental oncology.
D. A. Tzerkovsky +2 more
doaj +1 more source
Regulatory Mechanisms in Biosystems, 2018 We carried out the clinical validation of pathogenetically substantiated protocols for the treatment of female dogs with tumour lesions of the mammary gland.
D. D. Bely +5 more
doaj +1 more source
Protein Kinase C beta in the tumor microenvironment promotes mammary tumorigenesis
Frontiers in Oncology, 2014 Protein kinase C beta (PKCβ) expression in breast cancer is associated with a more aggressive tumor phenotype, yet the mechanism for how PKCβ is pro-tumorigenic in this disease is still unclear.
Julie A Wallace +11 more
doaj +1 more source
Canine, Feline, and Murine Mammary Tumors as a Model for Translational Research in Breast Cancer
Veterinary SciencesIn veterinary medicine, mammary tumors are the most common neoplasms in female dogs and the third most frequent in cats, representing a significant challenge.
Geovanni Dantas Cassali +10 more
doaj +1 more source
Study of histopathological changes of cat’s eyes as a model of malignant neoplasms development
Российский офтальмологический журналParaneoplastic syndromes are clinical and laboratory manifestations of the tumor process. Purpose: to study structural changes in domestic animals (cats) as a model for the development of malignant neoplasms of various origins and localizations based on ...
D. A. Vilmis +2 more
doaj +1 more source
Environment InternationalBackground: More than ten years ago, the World Health Organization’s (WHO) International Agency for Research on Cancer (IARC) published a monograph concluding there was limited evidence in experimental animals for carcinogenicity of Radio Frequency ...
Meike Mevissen +7 more
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