Results 91 to 100 of about 190,981 (166)

Exploratory Research of Intraductal Chemotherapy to Control the Focal Breast Lesion of Breast Cancer. [PDF]

Breast Cancer (Dove Med Press)
Lin X, Li X, Wei Q, Yuan H, Zhong M, Qiao J, Gong J, Li Y.   +7 more
europepmc   +1 more source

Comparative Digital Estrogen Receptor Alpha (ERα) Expression Analysis in Benign and Malignant Prostate Tissue of Men and Dogs

The Prostate, Volume 86, Issue 5, Page 568-581, April 2026.
ABSTRACT Background The dog is the only large mammal, other than humans, that commonly develops spontaneous prostate cancer (PCa) and is, therefore, considered a valuable model for comparative studies. Estrogens are critical for normal prostate development and contribute to prostatic carcinogenesis in men.
Jennifer Lothion‐Roy, Leonore Aeschlimann, Lea Anna Hiller, Sven Rottenberg, Nigel P. Mongan, Catrin S. Rutland, Emad Rakha, Alexander Dean, Mark A. Rubin, Simone de Brot   +9 more
wiley   +1 more source

Aging-associated differences in mammary tumor-initiating populations and immune evasion pathways in breast cancer. [PDF]

Proc Natl Acad Sci U S A
Yan P, Bui T, Rojas Jimenez E, Kuang Y, Xu S, P Paweletz C, Haimov H, Sklartz M, Cohen O, McAllister SS, Polyak K.   +10 more
europepmc   +1 more source

CMLPS-N1: a novel preclinical cell line model for canine mammary tumor and its application in therapeutic screening. [PDF]

Vet Q
Wang X, Zhou H, Zhang Q, Liu Y, He L, Li W, Ma B, Luo L, Guo L, Qiu C.   +9 more
europepmc   +1 more source

Trefoil Factor‐3 Is a Hypoxia‐Triggered Pro‐Tumorigenic Factor in Hepatoblastoma

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background & Aims Hepatoblastoma (HB) is the most common malignant liver tumour in children. Despite improved survival in low‐risk disease, outcomes for advanced or relapsed HB remain poor, emphasising the need for new therapeutic targets.
Luz A. Martínez‐Pérez, M. Ujue Latasa, Iker Uriarte, Amaya López‐Pascual, Jasmin Elurbide, Pavel Strnad, Sona Frankova, Eva Sticova, Ondrej Fabian, Maria Arechederra, Eva Santamaria, Josepmaria Argemi, Bruno Sangro, Beatrice Foglia, Maurizio Parola, Melva Gutiérrez‐Angulo, Stefano Cairo, Ramón Bataller, Pau Sancho‐Bru, Maria L. Martinez‐Chantar, Jose J. G. Marin, Andrea Castaneda, Carolina Armengol, Carmen Berasain, Maite G. Fernandez‐Barrena, Matias A. Ávila   +25 more
wiley   +1 more source

Promotion of breast cancer by the DNPH1 enzyme. [PDF]

iScience
Oh S, Sui Y, Shin S, Janknecht R.
europepmc   +1 more source

Evaluating the Efficacy of Polyphenol‐Enriched Plant Extracts and Pathway Modulators in the Bone Marrow to Suppress Breast Cancer Progression

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
The combined therapy decreased inflammatory and angiogenic signaling and altered bone marrow cell profiles linked to tumor dormancy, indicating a potential approach to limit disease progression and reduce relapse risk in breast cancer. ABSTRACT Disseminated tumor cells (DTCs) in the bone marrow can survive in a dormant state and later reawaken to drive
Hayarpi Javrushyan, Gayane Petrosyan, Marika Mróz, Barbara Kusznierewicz, Yem Alharithi, Mikayel Ginovyan, Alina Maloyan, Nikolay Avtandilyan   +7 more
wiley   +1 more source

Spermine Oxidase Serves as a Key Functional Node in Microbial Dysbiosis-Induced Breast Carcinogenesis. [PDF]

Cancer Res
Nandi D, Parida S, Verma D, Foley JR, Stewart TM, Korangath P, Thatikonda S, Siddharth S, Wu Q, Yi M, Bishai W, Ivkov R, Sears CL, Casero RA, Sharma D.   +14 more
europepmc   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

International Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak, Sabine Heublein, Verena Thewes, Lukas Wagener, Constantin Pixberg, Carlo Fremd, Laura Michel, Christian Maurer, Lars Buschhorn, Nicola Dikow, Fangyoumin Feng, Stefan Fröhling, Christel Herold‐Mende, Steffen Hirsch, Chen Hong, Daniel Hübschmann, Lena Jassowicz, Polina Kozyulina, Katrin Pfütze, Richard F. Schlenk, Hans‐Peter Sinn, Katharina Smetanay, Christoph Springfeld, Albrecht Stenzinger, Celina Wagner, Stephan Wolf, Andreas Trumpp, Dirk Jäger, Oliver Zivanovic, Marc Zapatka, Andreas Schneeweiss, Peter Lichter   +31 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, Volume 20, Issue 3, Page 668-687, March 2026.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source