Results 81 to 90 of about 195,634 (228)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley +1 more source
The GH-IGF-I axis and breast cancer
, 2012 MD (Res)Breast cancer remains one of the most common causes of death amongst women today. Worldwide approximately 1.3 million women are diagnosed as having breast cancer every year.
Laban, Christiana
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Measurement of physiological variables by dynamic Gd-DTPA enhanced MRI [PDF]
, 2003 Abnormal angiogenesis is characterised by the alteration of physiological variables such as capillary permeability and fractional volume of the extravascular extracellular space.
Radjenovic, Aleksandra
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Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases
The Laryngoscope, EarlyView.ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen +3 more
wiley +1 more source
Tumour–stroma interactions in an organotypic culture model of pancreatic cancer
, 2011 PhDPancreatic cancer is characterised by an intense fibrotic, or desmoplastic, stroma, which contributes to tumour progression. Three-dimensional in vitro culture models incorporating this non-tumour component may more closely recapitulate the ...
Froeling, Fieke E.M.
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Veterinary Record, EarlyView.Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik +2 more
wiley +1 more source
, 2018 Tese de Doutoramento em Ciências VeterináriasAs neoplasias de mama quimicamente induzidas pelos agentes carcinogénicos 7,12-dimetilbenz (a) antraceno (DMBA) e 1-metil-1-nitrosureia (MNU) em ratos têm sido frequentemente utilizadas como modelo para o ...
Alvarado Muñoz, Antonieta María
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A case of canine urothelial carcinoma of the urinary bladder with skull and skeletal metastases
Australian Veterinary Journal, EarlyView.Canine urinary bladder neoplasia is uncommon, representing less than 1% of canine neoplasms. Amongst cases of urinary bladder neoplasia in dogs, primary urothelial carcinoma is the most frequent. Urothelial carcinomas are malignant invasive tumours which tend to be slow growing and metastasise late.
A Teh, T Sima, E Shinozaki, R Malik
wiley +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
Preclinical pharmacology and clinical uses of topotecan
, 1999 Topotecan, a soluble semisynthetic derivative of camptothecin, is a specific inhibitor of topoisomerase I and is endowed of potent antiproliferative effect in vitro and in vivo on tumoral cell lines as well as on endothelial cells. Moreover, topotecan is
DEL TACCA M +2 more
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