Results 61 to 70 of about 196,671 (187)

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Australia's Three System Approach to Mammographic Image Quality Assessment

Journal of Medical Radiation Sciences, EarlyView.
Mammographic image evaluation in Australia remains constrained by the use of fragmented, subjective, and largely unevaluated systems. The continued use of the Perfect (P), Good (G), Moderate (M), Inadequate (I) (PGMI) image evaluation system (IES) framework despite concerns around its validity and reliability reflects a perceived practical utility and ...
Kelly Bentley‐Spuur, Minh T. Chau
wiley   +1 more source

Breast Cancer‐Derived AZU1 Educates Neutrophils to Promote Tumor Progression and Metastasis Through PAD4‐Dependent Extracellular Trap Formation

Molecular Carcinogenesis, EarlyView.
ABSTRACT Neutrophil extracellular traps (NETs) play crucial roles in cancer progression, but their regulatory mechanisms in breast cancer remain poorly understood. We developed a NETs‐related prognostic risk model using TCGA breast cancer data and identified key biomarkers through bioinformatics analysis.
Zhen Huang, Zhe Wu, Guiyue Zhu, Fangyu Qiu, Lihui Li, Yujie Xie, Chunyu Wei, Yinhua Pan, Quanqing Zou, Yuntian Tang   +9 more
wiley   +1 more source

Normal tissue complication probability models of late cardiopulmonary toxicity following deep inspiration breath hold for breast cancer adjuvant radiotherapy

Precision Radiation Oncology, EarlyView.
Deep inspiration breath hold (DIBH) markedly cuts heart and left lung radiation doses during left‐sided breast cancer radiotherapy. The normal tissue complication probability (NTCP) model further confirms lower predicted cardiopulmonary toxicities versus free breathing (FB), potentially improving patients’ quality of life.
Lin Lin, Liang Liu, Zhengxin Gao, Yaling Hong, Qing Gong, Zhan Yu, Xue Liu, Qiaoying Hu, Yongqiang Li, Shen Fu, Qi Yu   +10 more
wiley   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

A Droplet‐Microarray Platform for Multiplex Profiling of Breast Cancer Exosome Subtypes in Patients’ Blood Plasma Samples

Small, EarlyView.
This study presents a droplet‐microarray platform integrated with a DNase I‐assisted MoS2 FRET aptasensor for multiplexed profiling of breast cancer subtypes’ exosomes from patients’ plasma. By targeting HER2, MUC1, and CD44, the system enables sensitive detection and accurate discrimination of luminal A, HER2‐positive, and triple‐negative subtypes ...
Yi Liu, Ruolin Zhang, Jialei Song, Meng Xiao, Yue Meng, Zhiyang Li, Jingyu Shi, Yunyan Tai, Bing Gu, Mo Yang   +9 more
wiley   +1 more source

Systemic redox imbalance correlates with clinical aggressiveness and poor prognosis in canine inflammatory mammary carcinoma. [PDF]

Front Vet Sci
Fontes TN, Hielm-Björkman A, Vieira-Filho CHDC, de Carvalho VMP, Silva LP, de Oliveira VAP, Canuto GAB, de Sá HC, de Moura FBC, Barrouin-Melo SM, Fonseca-Alves CE, Estrela-Lima A.   +11 more
europepmc   +1 more source

Stress‐Adaptive Biomaterials With Tunable Yielding Architectures Regulate Organoid Morphogenesis

Small, EarlyView.
Granular hydrogels are developed to tune the yield stress levels at which 3D tissue culture matrices undergo plastic deformation. We use these materials to regulate growth‐induced stresses, with demonstrable effects on cancer spheroid invasion and brain organoid morphogenesis.
James P. W. Reeves, Sabra Rostami, Mostafa Rammal, Andrei Bocan, Paula Lépine, Matthew J. Harrington, Thomas M. Durcan, Christopher Moraes   +7 more
wiley   +1 more source

Case Report: Two cases of mammary intraductal papillary adenomas in nulliparous aged dairy cattle. [PDF]

Front Vet Sci
Fatola OI, Balkema-Buschmann A, Groschup MH, Ulrich R.   +3 more
europepmc   +1 more source

Theranostic π Electron‐Stabilized Polymeric Micelles for PET Imaging‐Guided Drug Delivery to Tumors

Small, EarlyView.
Cancer nanomedicine efficacy is limited by heterogeneous nanoparticle accumulation in tumors. Nuclear imaging offers non‐invasive, patient‐ and lesion‐specific visualization and quantification of nanoparticle uptake. We present a positron emission tomography (PET)‐imageable micelle platform for direct quantification of nanoparticle accumulation and ...
Alec Wang, Alexandru Florea, Jan‐Niklas May, Zaheer Ahmed, Karolin Roemhild, Thomas Hansen, Rahaf Mihyar, Armin Azadkhah Shalmani, Laura Schäfer, Karolin Becker, Masoud Sadeghzadeh, Eva M. Buhl, Sven Thoröe‐Boveleth, Susanne Lütje, Agnieszka Morgenroth, Fabian Kiessling, Jochen Maurer, Josbert M. Metselaar, Yang Shi, Felix M. Mottaghy, Quim Peña, Twan Lammers   +21 more
wiley   +1 more source