Results 111 to 120 of about 218,839 (237)

Comparative Digital Estrogen Receptor Alpha (ERα) Expression Analysis in Benign and Malignant Prostate Tissue of Men and Dogs

The Prostate, EarlyView.
ABSTRACT Background The dog is the only large mammal, other than humans, that commonly develops spontaneous prostate cancer (PCa) and is, therefore, considered a valuable model for comparative studies. Estrogens are critical for normal prostate development and contribute to prostatic carcinogenesis in men.
Jennifer Lothion‐Roy, Leonore Aeschlimann, Lea Anna Hiller, Sven Rottenberg, Nigel P. Mongan, Catrin S. Rutland, Emad Rakha, Alexander Dean, Mark A. Rubin, Simone de Brot   +9 more
wiley   +1 more source

Chemoprevention of DMBA‐Induced Mammary Tumors in Rats by a Combined Regimen of Alpha‐Tocopherol, Selenium, and Ascorbic Acid

The Breast Journal, 2000
M. Dias, E. Sousa, S. Cabrita, J. Patrício, C. Oliveira   +4 more
semanticscholar   +1 more source

Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth Cohort

Allergy, EarlyView.
This study investigates whether partial colostrum feeding (PCF) due to formula supplements in the first 3 days increases the risk of food allergy beyond cow's milk. PCF infants showed increased risk of peanut allergy and multiple food allergies compared to exclusively colostrum‐fed (ECF) infants.
Maheshwar Bhasin, Matthew Cooper, Patricia Macchiaverni, Ravisha Srinivas Joys, Therese A. O'Sullivan, Jeffrey A. Keelan, Carina Venter, Debra J. Palmer, Adrian J. Lowe, Susan L. Prescott, Desiree Silva, Valerie Verhasselt   +11 more
wiley   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Network Analysis of Predicted Therapeutic Symptoms in National Health Insurance Herbal Prescriptions. [PDF]

Life (Basel)
Jang S, Lee A, Kho C.
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Every Tumour Counts: A Comprehensive Overview of Canine Oncology in Portugal. [PDF]

Animals (Basel)
Brilhante-Simões P, Lopes R, Delgado L, Silva A, Pires I, Marcos R, Queiroga F, Prada J.   +7 more
europepmc   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Altered microRNA profiles and associated pathways in canine mammary adenocarcinoma. [PDF]

Sci Rep
Huniadi M, Nosalova N, Hornakova L, Petrouskova P, Kalinaj B, Mesarosova B, Cente M, Kubatka P, Hornak S, Cizkova D.   +9 more
europepmc   +1 more source

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance

Cancer Science, EarlyView.
In this study, we focused on SUMOylation, a posttranslational modification, and investigated the importance of its consensus sequence in MAFK. We demonstrated that the non‐SUMOylation mimic mutant MAFK (EA) impairs MAFK‐induced EMT, cellular migration and invasion, tumor and sphere formation, acquisition of stem‐like properties, and drug resistance ...
Thuy Linh Dang Cao, Yukari Okita, Reon Yahatabara, Manar A. Elhinnawi, Nuriza Ulul Azmi, Thanasis Poullikkas, Hozumi Motohashi, Mitsuyasu Kato   +7 more
wiley   +1 more source