Intratumoral dendritic cell immunotherapy controls dissemination of metastasis-initiating cancer cells, even in patients with metastatic breast cancer. [PDF]
Soyano A +12 more
europepmc +1 more source
Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin +10 more
wiley +1 more source
Cancer Across Domestic Animals: A Descriptive Review from the Veterinarian's Perspective. [PDF]
Giuliano A +8 more
europepmc +1 more source
Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles +6 more
wiley +1 more source
Systematic review and network meta-analysis of the effects of plant active substance on quality of life in breast cancer patients. [PDF]
Wang L +9 more
europepmc +1 more source
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan +14 more
wiley +1 more source
The Vietnamese swine as a translational model of invasive ductal carcinoma of the breast. [PDF]
Vera-Tizatl CE +6 more
europepmc +1 more source
ABSTRACT Canine hepatocellular carcinoma (HCC) requires further molecular characterization to identify diagnostic and therapeutic targets, and to establish whether dogs with this condition can model the human disease. Accordingly, we aimed to identify differentially expressed genes (DEGs) in canine HCC and evaluate cross‐species transcriptomic ...
Mohammad Arif +8 more
wiley +1 more source
Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis. [PDF]
Williams AE +14 more
europepmc +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source

