Results 61 to 70 of about 4,942,293 (176)

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Mammary-like adenocarcinoma of the vulva associated to Paget's disease: a case report

The Pan African Medical Journal, 2014
Mammary-like adenocarcinoma of the vulva associated to Paget's disease is exceedingly rare. So, it is very important to perform all the pathological and immunohistochemical investigations to achieve differential diagnosis from both a metastatic lesion ...
Sawsen Meddeb, Mohamed Salah Rhim, Sarra Mestiri, Mouna Kouira, Mohamed Bibi, Hedi Khairi, Mohamed Tahar Yacoubi   +6 more
doaj   +1 more source

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts [PDF]

, 2010
Introduction: Amniotic fluid harbors cells indicative of all three germ layers, and pluripotent fetal amniotic fluid stem cells (AFSs) are considered potentially valuable for applications in cellular therapy and tissue engineering.
Bernd Groner, Vafaizadeh, Vida, Groner, Bernd, Petra AB Klemmt, Vida Vafaizadeh, Klemmt, Petra A. B.   +5 more
core   +1 more source

Axillary Breast Cancer Masquerading as Extramammary Paget Disease after Bilateral Total Mastectomy: A Case Report

Case Reports in Dermatology
Introduction: Mammary Paget disease (MPD) and extramammary Paget disease (EMPD) are distinct conditions typically differentiated by anatomical location: MPD occurs on the breast and is indicative of underlying breast carcinoma, while EMPD ...
Michael M. Ong, Hadar K. Shimshon, Leore Lavin, Hesham Alshaikh, Andrea Moy, Anthony Rossi   +5 more
doaj   +1 more source

Single‐Center Epidemiological Analysis of Malignant Transformation With Skin Ulcers in Outpatients

International Wound Journal, Volume 23, Issue 1, January 2026.
ABSTRACT Investigate the epidemiological characteristics of outpatients initially diagnosed with skin ulcers who were ultimately confirmed to have cutaneous malignant tumours, and provide a diagnostic and therapeutic basis for the occurrence of secondary diseases in chronic wounds.
Yaoyao Kong, Haixia Wang, Nan Cao, Pengcheng Huai, Zhenzhen Wang, Chaoqi Zuo, Xueqing Wang, Yilei Wu, Yongxia Liu, Shengli Chen, Hong Liu, Guangliang Zhang   +11 more
wiley   +1 more source

Extramammary Paget disease of the vulva with underlying mammary-like lobular carcinoma: a case report and review of the literature

, 2015
Extramammary Paget disease of the vulva accounts for 1%–2% of the neoplasms of the anogenital area. Very rarely, extramammary Paget disease of the vulva has been associated with an underlying mammary-like carcinoma, usually ductal, extremely rarely mixed
Milikowski, Clara, Yu, Wendong, Villada, Gabriel, Farooq, Uzma, Diaz, John Paul   +4 more
core   +1 more source

Enfermedad de Paget de la mama sin carcinoma ductal asociado: reporte de caso y revisión de la literatura

Revista Colombiana de Obstetricia y Ginecología, 2019
Objetivo: presentar un caso de Enfermedad de Paget (EP) mamaria sin carcinoma ductal asociado y realizar una revisión de literatura respecto a su diagnóstico y tratamiento.
Liseth Johana Matamoros-Parra, Miguel Andrés Vertel-Velásquez, Gloria Eugenia Camargo-Villalba   +2 more
doaj   +1 more source

Hormonal Environment and HER2 Status in Extra-Mammary Paget’s Disease (eMPD): A Systematic Literature Review and Meta-Analysis with Clinical Considerations

Diagnostics, 2020
Background. Extra-mammary Paget’s disease (EMPD) is a rare neoplasm of epithelial origin, whose precise incidence is not clear. Starting from what is already known, we performed a systematic review and meta-analysis to investigate in male and female ...
Giuseppe Angelico, Angela Santoro, Frediano Inzani, Patrizia Straccia, Damiano Arciuolo, Antonino Mulè, Michele Valente, Saveria Spadola, Nicoletta D’Alessandris, Giorgia Garganese, Federica Cianfrini, Alessia Piermattei, Giovanni Scambia, Gian Franco Zannoni   +13 more
doaj   +1 more source

Cutaneous Metastasis: A Retrospective Clinicopathological and Prognostic Analysis of 62 Patients From a Tertiary Center in China

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Cutaneous metastases are uncommon but clinically significant manifestations of internal malignancies and may indicate advanced disease or, in certain cases, represent the initial sign of cancer. Their variable clinical and histopathologic presentations can pose diagnostic challenges, particularly when the primary tumor is unknown.
Qiannan Jia, Xinran Li, Jun Li, Suraiya Saleem   +3 more
wiley   +1 more source