Results 71 to 80 of about 4,942,293 (176)

The Roles of MicroRNAs, Oncogenes, and Tumor Suppressor Gene Molecular Subtypes of Breast Cancer: Therapeutic Potential of Pharmaceutical and Natural Products

International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Background Breast cancer (BC) is the most common malignancy among women, with 2.3 million new cases and over 670,000 deaths annually. Despite advances in detection and therapy, relapse, metastasis, and resistance remain significant challenges. Tumor suppressor genes (TSGs) regulate abnormal cell division, whereas oncogenes, which arise from proto ...
Md. Sadikuj Jaman, Md. Maniruzzaman, Md. Rokibul Hasan Bhuiyan, Md Shajedul Haque, Irfan Ahmad   +4 more
wiley   +1 more source

53 | MAMMARY PAGET DISEASE WITH OCCULT DCIS: A RARE MALE CASE

Dermatology Reports
Mammary Paget disease (MPD) is a rare intraepidermal adenocarcinoma accounting for 1–4% of breast malignancies, usually associated with underlying ductal carcinoma in situ (DCIS) or invasive carcinoma.
Associazione Dermatologi-Venereologi Ospedalieri Italiani e della Sanità Pubblica
doaj   +1 more source

Patterns of Postmastectomy Radiotherapy in Immediate Breast Reconstruction—Results From the iBRA‐2 Cohort Study

International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Purpose Long‐term data indicate that postmastectomy radiotherapy (PMRT) is associated with improved overall survival in node‐positive breast cancer patients. Immediate breast reconstruction (IBR) remains controversial in the context of planned PMRT, but rates of IBR are increasing.
Tim Rattay, Adam Trickey, Rachel L. O’Connell, Rajiv V. Dave, Joanna Skillman, Nicola L. P. Barnes, Matthew D. Gardiner, Chris Holcombe, Shelley Potter, Ivana Ribeiro   +9 more
wiley   +1 more source

Expression of Desmogleins in Paget Cells of Mammary and Extramammary Paget's Disease.

The Kurume Medical Journal, 1997
Sagebiel (1969) electronmicroscopically observed that desmosomes are present between adjacent Paget cells, as well as between Paget cells and adjacent keratinizing epidermal cells. Desmosomes contain the proteins desmoglein (Dsg) and desmocollin as their transmembrane components, and Dsg has three isotypes.
MORI, OSAMU, KARASHIMA, TADASHI, MATSUO, KEIZO, HASHIMOTO, TAKASHI   +3 more
openaire   +3 more sources

Enhancing the Anticancer Efficacy of Polyphenols Through Lipid‐Based and Polymeric Nanoparticle Delivery Systems in Triple‐Negative Breast Cancer (TNBC)

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Breast cancer is the most common cancer among women. Triple‐negative breast cancer (TNBC) lacks hormone receptors and human epidermal growth factor receptor 2 expression and has aggressive behavior and poor prognosis; therefore, it has significant limitations and challenges in its treatment.
Nooshin Goudarzi, Ensiyeh Bahadoran, Masood Alaei, Kimia Taebi, Arian Ashrafzadeh, Arash Keshavarz Shahbaz, Sanaz Keshavarz Shahbaz, Munmun Bardhan   +7 more
wiley   +1 more source

Enfermedad de Paget extramamaria de localización escrotal [PDF]

, 2003
La enfermedad de Paget extramamaria es un adenocarcinoma poco frecuente de la piel, descrita por primera vez por Cracker en 1889 en un caso de localización en pene y escroto.
Acosta, Jinneth, Jaramillo, Roberto, Fierro, Eduardo   +2 more
core  

Violet Paget (Paris, France) to Henry Paget

, 1870
8th--a frightening mob gathered outside the Paget\u27s windows in a noisey patriotic demonstration against the Prussians ; 9th--more citizen uprising finally subdued by new political appointments; the Paget-Hamilton household in a state of great ...
Lee, Vernon, (Violet Paget), Paget, Henry   +1 more
core   +3 more sources

A Case Report of Short‐Term Metastasis After Surgery for Mammary Paget's Disease

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Mammary Paget's disease (MPD) with ductal carcinoma in situ (DCIS) pathology can metastasize rapidly. HER2‐positive status likely drives aggression, warranting early postoperative systemic imaging and close surveillance. Anti‐HER2 agents require proactive toxicity management.
Chao Wang, Baiyi Yan, Jing Wang, Jiahui Zhou, Dongxu Li, Xiaofang Gao, Yong Pan   +6 more
wiley   +1 more source

Paget disease.Three cases of mammary Paget disease.

Skin Cancer, 1991
最近10年間に当科で経験した乳房Paget病の3例を報告した。症例1は34歳女性, 右乳頭とその周辺の硬く腫脹した紅色局面。症例2は69歳女性, 点状の鱗屑を付する右乳頭の腫脹。症例3は64歳女性, 左乳頭と周辺乳輪に厚い痂皮を付する紅色局面。組織学的に症例1, 2は面皰癌の所見が認められたが, 症例3は異型な乳管を認めるのみであった。症例2は臨床的に湿疹様の軽微な変化しか呈しておらず早期の生検の必要性を認識した。
openaire   +2 more sources

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, Volume 9, Issue 11, November 2025.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source