Results 171 to 180 of about 1,873,134 (303)

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

Extracellular vesicles from canine mammary tumor cells promote macrophage M2 polarization and enhance tumor progression. [PDF]

Vet Res Commun
Chi NK, Kim SH, Lim GH, Song KH, An JH, Ryu MO, Seo KW.   +6 more
europepmc   +1 more source

Subtype‐specific prognostic relevance of IL6 in basal‐like breast cancer and modulation of IL6 expression by nanobacteria‐like particles in MDA‐MB‐231 cells

Precision Medical Sciences, EarlyView.
High IL6 expression correlates with shorter relapse‐free survival in the basal‐like breast cancer subtype. Nanobacteria‐like particles (NB‐LPs) significantly reduce breast cancer cell viability and IL6 expression levels in MDA‐MB‐231 cells. Abstract Breast cancer is one of the most prevalent malignancies among women worldwide.
Fateme Nikakhtar, Masoumeh Nezhadali, Behnaz Esfandiari   +2 more
wiley   +1 more source

Antitumor Effects of <i>Juncus effusus</i> L. subsp. <i>effusus</i> in a Mammary Tumor Model: Regulation of ERα, p53, PCNA, and HIF-1α. [PDF]

Molecules
Ergin İ, Demirel MA, Süntar İ, Akarca Dizakar SÖ, Tugay O, Taban K, Şenel OO.   +6 more
europepmc   +1 more source

HER2‐Targeted AIE Nanotheranostics Overcome SHR‐A1811 Resistance via Immunogenic Pyroptosis and Tumor‐Associated Macrophage Reprogramming in Breast Cancer

Small, EarlyView.
HER2‐targeted AIE780‐A1811 nanoparticles self‐assemble via amide coupling of a mitochondria‐directed photosensitizer with the ADC SHR‐A1811. Upon 660 nm irradiation, they generate ROS, photothermal effects, and controlled drug release, inducing immunogenic pyroptosis and M2‐to‐M1 macrophage reprogramming. This dual action remodels the immunosuppressive
Xiaohong Liu, Nisha Wu, Zaihui Peng, Guozhi Zhang, Lin Ren, Qiuyun Li, Jie Xiao, Jing He, Yuxiuzi Xiao, Li Ma, Yi Zhang, Ying Gong, Xiaowei Qi   +12 more
wiley   +1 more source

β-lapachone impairs viability, migration, and epithelial-mesenchymal transition in mammary tumor spheroids. [PDF]

BMC Cancer
Coelho LL, Vianna MM, da Silva DM, Gonzaga BMS, Ferreira RR, Coutinho CMLM, Magalhães FCM, Maria EJ, de Oliveira RR, Manso PPA, de Carvalho MA, Vargas FR, Garzoni LR.   +12 more
europepmc   +1 more source

Alkyl chain elongation engineering: Unlocking high‐brightness NIR‐II O‐xanthene dyes for in vivo bioimaging

Smart Molecules, EarlyView.
O‐xanthene–based fluorophore enhanced fluorescence quantum yield and brightness were achieved by extending the N‐alkyl chain on the aniline donor. Abstract NIR‐II fluorescent probes are powerful tools for advanced imaging, with performance governed by molar extinction coefficient (ε), quantum yield (Φ), and brightness (ε × Φ).
Yu Zhao, Hong Zhang, Ruirui Zhang, Wenli Xia, Zhouyu Wang, Jie Chen, Xiaoqi Yu, Kun Li   +7 more
wiley   +1 more source

Inside the Tumor: Decoding the Feline Mammary Tumor Microenvironment and Its Prognostic Value-A Review. [PDF]

Vet Sci
Rodrigues-Jesus J, Canadas-Sousa A, Vilhena H, Dias-Pereira P.   +3 more
europepmc   +1 more source

Thrombocytosis and tumour distribution predict outcome in dogs with hepatocellular carcinoma: A multi‐institutional retrospective analysis

Veterinary Record, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik, MacKenzie A. Pellin, Dawn M. Clarke   +2 more
wiley   +1 more source

Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth. [PDF]

Mol Ther
Tocheny CE, Buchwald JE, Dahlke CD, Fakih HH, Morgan JS, Summers A, Silva CA, Jackson SO, Lee JS, Card MA, Echeverria D, Peterson C, Mercurio AM, Khvorova A, Shaw LM.   +14 more
europepmc   +1 more source