Results 191 to 200 of about 1,873,134 (303)

Human betaretrovirus (HBRV), homologous to mouse mammary tumor virus (MMTV), and human breast cancer: a significant epidemiological association. [PDF]

Retrovirology
Saeedi-Moghaddam F, Saffarian N, Mozhgani SH.   +2 more
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Development and computational analysis of high dimensional spectral flow cytometry data for the resolution of innate lymphoid cells in the mammary tumor microenvironment. [PDF]

Front Immunol
Seo H, Xue J, Huang Q, Kinzel M, Verma A, Huynh N, Jamila Ikra Z, Mahoney DJ, Lee J, Morrissy S, Jacquelot N.   +10 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression. [PDF]

Cancer Prev Res (Phila)
Smith LA, Craven DM, Ho AN, Glenny EM, Rezeli ET, Carson MS, Paules EM, Fay M, Cozzo AJ, Hursting SD, Coleman MF.   +10 more
europepmc   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor. [PDF]

JCI Insight
Li X, Rossing M, Moisés da Silva A, Bose M, Gudjónsson T, Benada J, Thatte J, Johansen JV, Börcsök J, van der Gulden H, Song JY, Menezes R, Tajik A, Sena L, Szallasi Z, Frödin M, Jonkers J, Nielsen FC, Sørensen CS.   +18 more
europepmc   +1 more source

Adding Intratumoral Antibody‐Photoabsorber Conjugate Improves Efficacy of Near‐Infrared Photoimmunotherapy (NIR‐PIT)

Cancer Science, EarlyView.
Intravenous (IV) or intratumoral (IT) cetuximab distribution in A431 tumor (essence of Figure 2). ABSTRACT Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer treatment that specifically kills target cells while sparing normal tissue. This treatment induces cancer cell death by activating a photoreactive dye with near‐infrared light in ...
Miyu Kano, Aki Furusawa, Seiichiro Takao, Makoto Kano, Motofumi Suzuki, Hiroshi Yamamoto, Shuhei Okuyama, Ko Kitamura, Peter L. Choyke, Hisataka Kobayashi   +9 more
wiley   +1 more source

Decitabine suppresses tumor growth by activating mouse mammary tumor virus and interferon-β pathways. [PDF]

Biomol Biomed
Johnson R, Brola A, Wycoff C, Wycoff W, Neumeyer S, Tuttle R, Light S, Li J, Christensen S, Liu Y.   +9 more
europepmc   +1 more source

Japanese Society for Hereditary Tumors Guidance: Hereditary Cancer Syndromes With Multigene Panel Testing, 2025 Edition

Cancer Science, EarlyView.
Schematic of the clinical algorithm for diagnosing hereditary cancer syndromes using MGPT. ABSTRACT In March 2025, the Japanese Society for Hereditary Tumors and the Ministry of Health, Labour and Welfare (MHLW) Research on Promotion of Cancer Control Program Grant Number JPMH 23EA1037 published the “Japanese Society for Hereditary Tumors Guidance ...
Reiko Yoshida, Akira Hirasawa, Issei Imoto, Tatsuro Yamaguchi, Kensuke Kumamoto, Momoko Araki, Arisa Ueki, Kenta Masuda, Yusaku Urakawa, Noriko Tanabe, Atsushi Watanabe, Makoto Hirata, Tomoyuki Aruga, Takeshi Kuwata, Yoshinaga Okugawa, Keika Kaneko, Hiroko Terui‐Kohbata, Megumi Matsumoto, Sayaka Ueno, Katsutoshi Oda, Hisako Ono, Akihiro Sakurai, Hirotaka Matsui, Gou Yamamoto, Hideki Yamamoto, Yasuko Yamamoto, Masachika Ikegami, Yusuke Ohkuma, Kazuhiko Shien, Shigenobu Suzuki, Shunsaku Takayanagi, Masahiko Tanabe, Hisashi Hasumi, Naohito Hatta, Hiroyoshi Hattori, Hiroyuki Matsubayashi, Wataru Yamagami, Masayoshi Yamada, Kazuyuki Oishi, Tomomi Oka, Shinya Oda, Yusuke Kobayashi, Kazuhiro Takekoshi, Takeshi Nakajima, Yoshiko Nakano, Yoshiko Nakayama, Fumiharu Miura, Yasuyuki Miyakura, Yoshiko Mori, Akiyo Yoshimura, Masato Yonamine, Kunitoshi Shigeyasu, Hiroko Fujita, Mashu Futagawa, Kouji Ohta, Junko Kawano, Tomoharu Tokutomi, Ayaka Sato, Takeshi Makabe, Tomoko Yoshihama, Miki Aitani, Kaori Kimura, Nabue Takaiso, Chikako Tomozawa, Yumie Hiraoka, Manami Matsukawa, Hideyuki Ishida   +66 more
wiley   +1 more source