Results 211 to 220 of about 1,873,134 (303)

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

Transcriptomic profiling of PBMCs from mammary tumor dogs reveals two distinct immune states. [PDF]

Am J Cancer Res
Lee KH, Lee D, Lee JW, Hwang HJ, Cho JY.
europepmc   +1 more source

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source

LncRNA LOC610012 Inhibits Canine Mammary Tumor Activity via the PTGS2/EP3 and GSK3β Signaling Pathways. [PDF]

Cells
Zhang B, He L, Wang X, Liu W, Li Y, Wang Y, Feng H, Li W, Qiu C.   +8 more
europepmc   +1 more source

Detection of NTRK1/2/3 rearrangements in pigmented spindle cell naevus of Reed: a comparative study of optimized pan‐TRK immunohistochemistry, FISH and RNA‐NGS

Histopathology, EarlyView.
Pigmented spindle cell nevus of Reed (PSCN) is a subtype of Spitz nevus mainly characterized by MYO5A::NTRK3 fusion. Our optimized pan‐TRK protocol stained 16/79 (20.3%) PSCNs (diffuse, granular, cytoplasmic staining of moderate intensity) and revealed high values of specificity (94.4%–96.2%) and positive predictive value (92.3%) for the detection of ...
Costantino Ricci, Barbara Corti, Sara Coluccelli, Giulia Calafato, Debora Anconelli, Francesco Vasuri, Martina Lambertini, Federico Venturi, Biagio Scotti, Alessia Grillini, Eugenia Franchini, Thais Maloberti, Antonio De Leo, Giovanni Tallini, Elisa Gruppioni, Annalisa Altimari, Michelangelo Fiorentino, Gerardo Cazzato, Emi Dika, Dario de Biase   +19 more
wiley   +1 more source

Comparative epigenomics to clinical trials in human breast cancer and canine mammary tumor. [PDF]

Anim Cells Syst (Seoul)
Jeong SJ, Lee KH, Cho JY.
europepmc   +1 more source

Immunomodulatory Peptide LW‐9 Enhances Doxorubicin Efficacy by Downregulating PD‐L1 and Promoting Intratumoral T‐Cell Responses in Murine Breast Cancer

Immunology, EarlyView.
LW‐9, a peptide derived from Phoneutria nigriventer venom, enhances antitumor immunity in a murine breast cancer model by remodelling the tumour microenvironment. Treatment reduces PD‐L1 expression while increasing CD3+ and GITR+ T‐cell infiltration, resulting in delayed tumour progression, particularly when combined with doxorubicin.
Ingrid Mayara Cavalcante Trevisan, Cibele Pereira Mariano, Sabrina Carvalho Brunelli, Gabriel da Silva Cordeiro, Jessika Takaki, Valquiria Aparecida Matheus, Liana Verinaud, Catarina Rapôso   +7 more
wiley   +1 more source

Limited Chemopreventive Effects of Oral Administration of Polyphenol-60 from Green Tea in the MNU-Induced Rat Mammary Tumor Model. [PDF]

Antioxidants (Basel)
Gal AF, Rugină D, Dumitraș DA, Tabaran AF, Matei-Lațiu MC, Andrei SM.   +5 more
europepmc   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

Effect of 2-methoxyestradiol on mammary tumor initiation and progression. [PDF]

Cancer Rep (Hoboken)
Peta KT, Durandt C, van Heerden MB, Joubert AM, Pepper MS, Ambele MA.   +5 more
europepmc   +1 more source