Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1. [PDF]
Chen M +7 more
europepmc +1 more source
Cell‐Migration Visualization: Task Taxonomy, Systematic Review and Research Agenda
We present an expert‐validated task taxonomy for cell migration analysis and a PRISMA‐based systematic review that maps visualization tools to the tasks they support and the techniques they employ. This synthesis identifies current gaps and outlines opportunities for future research in cell migration visualization.
Ana Carla Correia +3 more
wiley +1 more source
Genetic background and oncogenic driver determines the genomic evolution and transcriptomics of mammary tumor metastasis. [PDF]
Ross CR +7 more
europepmc +1 more source
Summary A 20‐year‐old warmblood gelding was referred for the evaluation of severe cervical stiffness and pain. Radiographic examination revealed marked arthropathy of the C3–C4 articular processes, with severe remodelling and narrowing of the C3–C4 intervertebral space.
F. Bonaspetti +4 more
wiley +1 more source
Propranolol enhances the oncolytic effect of newcastle disease virus on canine mammary tumor cell by modulating the IFN-I-mediated JAK-STAT signaling pathway. [PDF]
Zhu Y, Xu M, Li M.
europepmc +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
CEBPD regulates CD47 and MAP4K4 via chromatin accessibility in canine mammary tumor monocytes. [PDF]
Lee JW, Lee D, Shin KJ, Son KH, Cho JY.
europepmc +1 more source
A guide to transcriptional cyclin‐dependent kinases in cancer
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin +2 more
wiley +1 more source
Epigenetic control of cellular plasticity in breast cancer progression
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey +2 more
wiley +1 more source
Natural Product Epipyrone A from <i>Epicoccum nigrum</i> Exhibits Antiproliferative Activity on Canine Mammary Tumor Cells Through PI3K/Akt/mTOR Pathway Modulation. [PDF]
Longobardi C +8 more
europepmc +1 more source

