Results 151 to 160 of about 419,920 (305)

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam, Sushmitha Sriramulu, Asya Haider Muratoglu, Stephen Brown, Oudai Hassan, Benjamin Movsas, Haythem Ali, Steven Chang, Patrick Ha, Farzan Siddiqui, Shyam Nyati   +10 more
wiley   +1 more source

Cohort study of standardized treatment pathways by multidisciplinary tumor board decision making in patients with salivary gland malignancies

International Journal of Cancer, EarlyView.
What's New? The overall survival of patients with salivary gland malignancies has shown limited progress. Here, the authors evaluated the impact of establishing a multidisciplinary tumor board to ensure standardized diagnostic and treatment procedures at a certified cancer center.
Nils Feldmann, Gunnar Wichmann, Andreas Dietz, Markus Pirlich   +3 more
wiley   +1 more source

Metabolic Alterations in Canine Mammary Tumors. [PDF]

Animals (Basel), 2023
Tamarindo GH, Novais AA, Chuffa LGA, Zuccari DAPC.   +3 more
europepmc   +1 more source

A cost‐effectiveness analysis of breast cancer treatment in certified versus non‐certified hospitals in Germany

International Journal of Cancer, EarlyView.
What's New? This study is the first to quantify the cost‐effectiveness of breast cancer treatment in German Cancer Society‐certified hospitals using real‐world data from over 140,000 patients. Analysis on certification‐related costs and survival outcomes demonstrates that high‐quality multidisciplinary care at certified hospitals delivers substantial ...
Min‐Wai Lwin, Olaf Schoffer, Christoph Streissnig, Pauline Wimberger, Michael Gerken, Veronika Bierbaum, Christoph Bobeth, Martin Rößler, Patrik Dröge, Thomas Ruhnke, Christian Günster, Kees Kleihues‐van Tol, Theresa Link, Anton Scharl, Elisabeth C. Sturm‐Inwald, Karin Kast, Thomas Papathemelis, Olaf Ortmann, Monika Klinkhammer‐Schalke, Jochen Schmitt, Michael Schlander   +20 more
wiley   +1 more source

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

iMetaMed, EarlyView.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen, Hui Chen, Vijaya Raghavan, Jing Huang, Jin Wang   +4 more
wiley   +1 more source

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source

Doxorubicin as a Potential Treatment Option in Canine Mammary Tumors. [PDF]

Vet Sci, 2023
Gherman ML, Zanoaga O, Budisan L, Raduly L, Berindan-Neagoe I.   +4 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Machine learning-assisted detection of canine mammary tumors using serum autoantibody signatures. [PDF]

Vet Q
Lan B, Chang CY, Liu SW, Wu CC, Lai KM, Liu HP.   +5 more
europepmc   +1 more source

Sonographic localisation of lymph nodes suspicious of metastatic breast cancer to surgical axillary levels

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 119-138, March 2025.
Sonographic imaging is used to identify the presence, number and location of malignant lymph nodes. Axillary lymph nodes suspicious of harbouring breast cancer metastasis can be localised to three surgical axillary levels. This paper will unpack the axillary anatomy, muscular sonographic landmarks, surgical axillary lymph node levels and the ...
Michelle Fenech, Tracey Burke, Grace Arnett, Alisha Tanner, Natasha Werder   +4 more
wiley   +1 more source