Results 171 to 180 of about 419,920 (305)

The Importance of Ultrasonography in the Evaluation of Mammary Tumors in Bitches. [PDF]

open access: yesAnimals (Basel), 2023
Feliciano MAR   +6 more
europepmc   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

open access: yesMed Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang   +12 more
wiley   +1 more source

Inhibition of mTOR attenuates the initiation and progression of BRCA1-associated mammary tumors. [PDF]

open access: yesCancer Commun (Lond)
Baek HJ   +13 more
europepmc   +1 more source

Dynamic Contrast Enhanced—Magnetic Resonance Fingerprinting (DCE‐MRF) Improves Detection of Induced Vascular Perfusion Reduction in a Mouse Breast Cancer Model

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Dynamic contrast‐enhanced MRI (DCE‐MRI) can assess tumor perfusion using pharmacokinetic models. However, poor DCE‐MRI reproducibility from reliance on conventional T1‐weighted MRI has limited clinical translation. We evaluated whether Dynamic Contrast Enhanced‐Magnetic Resonance Fingerprinting (DCE‐MRF), which directly generates ...
Christina J. MacAskill   +15 more
wiley   +1 more source

Androgen Receptors in Human Breast Cancer and Female Canine Mammary Tumors. [PDF]

open access: yesMolecules
Vidović V   +5 more
europepmc   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

PD-1, PD-L1, and PD-L2 Expression as Predictive Markers in Rare Feline Mammary Tumors. [PDF]

open access: yesVet Sci
Franco M   +12 more
europepmc   +1 more source

Interpretable CRAM‑Enhanced Lightweight Dual‑Branch CNN for Real‑Time Breast Cancer Histopathology in Internet‑of‑Medical‑Things Environments

open access: yesSmall, EarlyView.
This study presents an interpretable, lightweight hybrid deep learning model for real‐time analysis of breast cancer histopathology in IoMT‐enabled diagnostic systems. By integrating MobileNetV2 and EfficientNet‐B0 with a novel contextual recurrent attention module (CRAM), the framework achieves near‐perfect accuracy while providing transparent Grad ...
Roseline Oluwaseun Ogundokun   +4 more
wiley   +1 more source

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