Results 231 to 240 of about 419,920 (305)

The Regulation and Function of Hippo/YAP Pathway in Cancer

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh, Ruchi Kakar, Seline Torkamboor, Yue Sun   +3 more
wiley   +1 more source

p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator. [PDF]

Cancer Res Commun
McDaniel JM, Morrissey RL, Dibra D, Patel LR, Xiong S, Zhang Y, Chau GP, Su X, Qi Y, El-Naggar AK, Lozano G.   +10 more
europepmc   +1 more source

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 1022-1035, April 2026.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles, Jyotirmoy Roy, Michael D. Brooks, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea, Sophia M. Orbach   +6 more
wiley   +1 more source

Enhancing the Anti-Tumor Efficacy of NK Cells on Canine Mammary Tumors through Resveratrol Activation. [PDF]

Animals (Basel)
Zhu T, Jin S, Tong D, Liu X, Liu Y, Zheng J.   +5 more
europepmc   +1 more source

Case Report of IgG4‐Related Autoimmune Pancreatitis

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This case presents a clear diagnosis with a complete chain of clinical evidence. Long‐term follow‐up revealed that, despite excellent disease control, the condition relapsed more than 6 months after discontinuation of glucocorticoids, with a tendency toward further progression.
Rui Yu, Shiyu Zhang, Yanping Zhao, Jingdong Xiao, Chuijie Wang, Yufeng Li, Ziting Mo, Xihan Zhu   +7 more
wiley   +1 more source

Detection of PIK3CA hotspot mutations in canine mammary tumors using droplet digital PCR: tissue validation and liquid biopsy feasibility. [PDF]

Sci Rep
Seung BJ, Sur JH.
europepmc   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, Volume 158, Issue 7, Page 1927-1940, 1 April 2026.
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Study on the therapeutic effect and some immune factors by methotrexate modified superparamagnetic nanoparticles in rat mammary tumors. [PDF]

Nanoscale Adv
Huang L, Zhao X, Zhang J, Zhang J, Liao W, Fan Y, Tang J, He Z, Gao F, Ouyang W.   +9 more
europepmc   +1 more source

Anti‐Cancer Effect of a New 5‐FU Derivative Containing Triazole‐Bearing Mannose (5‐FUD‐MAN) Against Human Breast Cancer Cells Through LC3B‐Mediated Cell Death

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 4, April 2026.
The anticancer activity of 5‐FU modified with mannose containing 1,2,3‐triazole compound in MCF‐7 breast cancer cells were revealed in this study. While 5‐FU caused cytotoxicity in both cancerous and healthy cells, 5‐FUD‐Man showed selective cytotoxicity.
Ebru Şanci, Azada Aliyeva, Buket Bakan, Mustafa Özkaraca, Erkan Halay, Kadir Ay, Tamer Karayildirim, N. Ulku Karabay Yavasoglu   +7 more
wiley   +1 more source

Preliminary Exploration of <i>MAGE-B1</i>, <i>-B4</i>, <i>-B5</i>, and <i>-B10</i> mRNA Expression in Canine Mammary Tumors in Dogs. [PDF]

Animals (Basel)
Srisawat W, Koonyosying P, Muenthaisong A, Sangkakam K, Varinrak T, Sthitmatee N.   +5 more
europepmc   +1 more source