Amyloid in Canine Mammary Tumors [PDF]
Veterinary Pathology, 1985 In canine mammary carcinomas, amyloid was present as amyloid-containing corpora amylacea and as local deposits between neoplastic epithelial cells or in stromal tissue. Histochemical staining methods revealed that this amyloid was not of the AA-type amyloid and contained tryptophan. The possible pathogenesis of this amyloid deposition is discussed.
J H, Vos, E, Gruys
openaire +2 more sources
Epidemiological study of canine mammary tumors: age, breed, size and malignancy
Austral Journal of Veterinary Sciences, 2018 A retrospective study was carried out on 858 female canine patients who were attended at the Surgery Service of the Clinical Veterinary Hospital of the University of Extremadura (Spain), during a period of 5 years (2008-2012).
Nieves Pastor +5 more
doaj +1 more source
Epidemiological Study of Mammary Tumors in Female Dogs Diagnosed during the Period 2002-2012: A Growing Animal Health Problem. [PDF]
PLoS ONE, 2015 Epidemiological studies enable us to analyze disease behavior, define risk factors and establish fundamental prognostic criteria, with the purpose of studying different types of diseases.
Yaritza Salas +3 more
doaj +1 more source
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. [PDF]
, 2016 Expression of the oncogenic transcription factor MYC is disproportionately elevated in triple-negative breast cancer (TNBC), as compared to estrogen receptor-, progesterone receptor- or human epidermal growth factor 2 receptor-positive (RP) breast cancer.
Anderton, Brittany +11 more
core +1 more source
Genetic mechanisms in Apc-mediated mammary tumorigenesis. [PDF]
PLoS Genetics, 2009 Many components of Wnt/beta-catenin signaling pathway also play critical roles in mammary tumor development, yet the role of the tumor suppressor gene APC (adenomatous polyposis coli) in breast oncongenesis is unclear.
Mari Kuraguchi +4 more
doaj +1 more source
Mammary stem cell research in veterinary science : an update [PDF]
, 2013 The mammary gland is an organ with a remarkable regenerative capacity that can undergo multiple cycles of proliferation, lactation, and involution. Growing evidence suggests that these changes are driven by the coordinated division and differentiation of
Borena, Bizunesh Mideksa +4 more
core +1 more source
Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells? [PDF]
, 2012 Field cancerization effects as well as isolated tumor cell foci extending well beyond the invasive tumor margin have been described previously to account for local recurrence rates following breast conserving surgery despite adequate surgical margins and
Benz, Christopher C +8 more
core +2 more sources
Folic acid supplementation promotes mammary tumor progression in a rat model.
PLoS ONE, 2014 Folic acid supplementation may prevent the development of cancer in normal tissues but may promote the progression of established (pre)neoplastic lesions.
Shaidah Deghan Manshadi +6 more
doaj +1 more source
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. [PDF]
, 2017 Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened collagenous stroma fosters malignant transformation of the tissue by increasing tumor cell tension to ...
Cassereau, L +11 more
core +2 more sources
The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression. [PDF]
, 2016 Basal-like breast cancers (BLBCs) are aggressive breast cancers associated with poor survival. Defining the key drivers of BLBC growth will allow identification of molecules for targeted therapy.
Brown, Powel H +6 more
core +5 more sources