Results 61 to 70 of about 12,911 (256)

Agent‐Based Computational Modeling of the Stochastic Dynamic Behavior of Actin Filaments Recapitulates the Homeostatic Cortical Array in Plant Epidermal Cells

open access: yesCytoskeleton, EarlyView.
ABSTRACT The homeostatic cortical actin array in plant cells plays important roles in fundamental processes, including intracellular transport, secretion, cell expansion, and cytoplasmic streaming. In response to diverse chemical and mechanical signals, the cortical array can remodel within minutes to assume new configurations or altered filament ...
June Hyung Kim   +4 more
wiley   +1 more source

Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent

open access: yesScientific Reports, 2021
The mechanisms through which cells of the host innate immune system distinguish commensal bacteria from pathogens are currently unclear. Toll-like receptors (TLRs) are a class of pattern recognition receptors (PRRs) expressed by host cells which ...
Sreeram Udayan   +8 more
doaj   +1 more source

Toward Establishing an Ideal Adjuvant for Non-Inflammatory Immune Enhancement

open access: yesCells, 2022
The vertebrate immune system functions to eliminate invading foreign nucleic acids and foreign proteins from infectious diseases and malignant tumors.
Tsukasa Seya   +2 more
doaj   +1 more source

Uso de membranas bacterianas como fuente para la elaboración de liposomas como adyuvantes [PDF]

open access: yes, 2012
La formulación de liposomas como adyuvantes a partir de membranas interna (MI) y externa (ME) de bacterias Gram(-) permite estimular al sistema inmune ya que incorporan patrones moleculares asociados a microorganismos (MAMPs) en su estructura ...
Sáenz Iturriaga, Leonardo   +2 more
core   +2 more sources

Microbial burden of periodontal diseases and its clinical application: The stage, grade, and furcation matter

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontal diseases are associated with dysbiotic oral microbial communities, but clinically applicable measures that reflect microbial burden across disease severity and progression remain limited. This study aimed to assess the oral microbial burden of periodontal diseases by evaluating salivary and subgingival lipopolysaccharide
Anbo Dong   +8 more
wiley   +1 more source

Structure Dependent-Immunomodulation by Sugar Beet Arabinans via a SYK Tyrosine Kinase-Dependent Signaling Pathway

open access: yesFrontiers in Immunology, 2018
There is much interest in the immunomodulatory properties of dietary fibers but their activity may be influenced by contamination with microbial-associated molecular patterns (MAMPs) such as lipopolysaccharide (LPS) and lipoteichoic acids, which are ...
Marjolein Meijerink   +13 more
doaj   +1 more source

Short-Chain Fatty Acid and FFAR2 Activation – A New Option for Treating Infections?

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The human innate immune system is equipped with multiple mechanisms to detect microbe-associated molecular patterns (MAMPs) to fight bacterial infections.
Katja Schlatterer   +8 more
doaj   +1 more source

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

open access: yesSmall, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang   +16 more
wiley   +1 more source

Regulation of T cell immunity in atopic dermatitis by microbes: The Yin and Yang of cutaneous inflammation

open access: yesFrontiers in Immunology, 2015
Atopic dermatitis (AD) is a chronic inflammatory skin disease predominantly mediated by T helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have been elucidated in detail, deciphering the impact of innate immunity in AD ...
Tilo eBiedermann   +3 more
doaj   +1 more source

Arabidopsis defense against Botrytis cinerea : chronology and regulation deciphered by high-resolution temporal transcriptomic analysis [PDF]

open access: yes, 2012
Transcriptional reprogramming forms a major part of a plant’s response to pathogen infection. Many individual components and pathways operating during plant defense have been identified, but our knowledge of how these different components interact is ...
Atwell, Susanna   +28 more
core   +3 more sources

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