Results 81 to 90 of about 1,069,430 (319)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

May Ray as an Artist and Photographer: Problems of Self-identification

open access: yesИзвестия Уральского федерального университета. Серия 2: Гуманитарные науки, 2018
This article considers the problems of self-identification by Man Ray (1890–1976) as a painter and photographer in the first half of the 20th century, the era of formation of a new aesthetic paradigm that included the de-mythologisation of the artist and 
Оlga Nikolayevna Averyanova
doaj   +1 more source

Pinhole-coronograph tracking control [PDF]

open access: yes
The pinhole occulter system, a space shuttle based experiment for the production of hard X-ray images taken primarily from the Sun is described. The system is a pinhole camera utilizing a deployable 50 m flexible boom for separating the pinhole from the ...
Greene, M.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The Cowl - v.23 - n.4 - Nov 02, 1960 [PDF]

open access: yes, 1960
The Cowl - student newspaper of Providence College. Volume 23, Number 4 - November 2, 1960.

core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Gallstone Ileus: Clinical Presentation of a Benign Mechanical Intestinal Obstruction

open access: yesCase Reports in Gastroenterology, 2008
Gallstone ileus is a rare cause of small bowel obstruction which usually presents in elderly female patients and which has been associated with high morbidity and mortality rates.
Eduardo E. Montalvo-Jave   +2 more
doaj   +1 more source

Ergonomic problems regarding the interactive touch input via screens in onboard and ground-based flight control [PDF]

open access: yes
A significant problem concerning the integration of display and switching functions is related to the fact that numerous informative data which have to be processed by man must be read from only a few display devices.
Gaertner, K. P., Holzhausen, K. P.
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

CHỌN TẠO GIỐNG LÚA CHẤT LƯỢNG CAO CHO ĐỒNG BẰNG SÔNG CỬU LONG GIAI ĐOẠN 2006-2008

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2010
Trước tình hình dịch hại do rầy nâu lan truyền trong các năm vừa qua, chọn giống lúa vượt trội về năng suất, phẩm chất, chống chịu rầy nâu, thích nghi vùng đất phù sa, phèn mặn là một thách thức đặt ra không nhỏ cho các nhà chọn tạo giống.
Phạm Thị Phấn   +3 more
doaj  

Home - About - Disclaimer - Privacy