Results 91 to 100 of about 1,667,290 (353)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

An exploration of the internal communication practices in hotels of Gauteng province, South Africa. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2018
This study was conducted to explore the communication practices in hotels. A cross-sectional survey research design was used in which self-administered questionnaires were used to collect data from seven employees representing different sections in the ...
J.J. Sibanyoni   +2 more
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Women Managers from Myths To Reality [PDF]

open access: yes
The role of women worldwide is undergoing a dramatic change. Women today share the podium with men in almost all the fields, be it in kitchen or in defence. Workingwomen are no longer a rarity and are now accepted as an integral part of the working force.
Parikh Indira J, Kollan Bharti
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

What do managers’ know? Examining experienced managers’ wisdom

open access: yes, 2015
Purpose: The paper critically examines the nature of managerial knowledge, highlights the limitations of formal managerial knowledge in informing managerial practice and demonstrates the role of alternative forms of knowledge, knowing and wisdom in ...
Black, Kate, Warhurst, Russell
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Where do public house managers come from ? Some survey evidence [PDF]

open access: yes, 2001
There is little evidence about British public house managers, despite an increase in their relative importance. This article outlines some key issues and reports on the results of a survey of managers in one region of a large leisure retail company.
Alistair Mutch, Mutch, A
core   +1 more source

Unlearning at the Individual Level: An Exploratory Case Study in a High Power Distance Country

open access: yesJournal of Innovation Management, 2018
This paper presents a case study that addresses factors that influence unlearning at the individual level. These factors were studied in a public sector organization located in a country characterized by high power distance.
Julieta Kaoru Watanabe Wilbert   +3 more
doaj   +1 more source

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