Dissection of the global responses of mandarin fish pyloric cecum to an acute ranavirus (MRV) infection reveals the formation of serositis and then ascites [PDF]
Journal of VirologyMandarin fish ranavirus (MRV), a new member of the species Ranavirus micropterus1, sharing over 98% whole-genome nucleotide identity with the well-known largemouth bass virus (LMBV), is a distinct member of the genus Ranavirus within the family ...
Wenfeng Zhang +7 more
doaj +6 more sources
Viral genomic methylation and the interspecies evolutionary relationships of ranavirus. [PDF]
PLoS PathogensRanaviruses are capable of infecting both wild and farmed fish, amphibians, and reptiles, leading to significant economic losses and ecological risks. Currently, ranaviruses have been found in at least 175 species spanning six continents.
Weiqiang Pan +6 more
doaj +6 more sources
The Interaction of Mandarin Fish DDX41 with STING Evokes type I Interferon Responses Inhibiting Ranavirus Replication [PDF]
Viruses, 2022 DDX41 is an intracellular DNA sensor that evokes type I interferon (IFN-I) production via the adaptor stimulator of interferon gene (STING), triggering innate immune responses against viral infection.
Xiao-Wei Qin +9 more
doaj +5 more sources
Development of a Highly Permissive Mandarin Fish (Siniperca chuatsi) Kidney Cell Line for Mandarin Fish Ranavirus Using a Single-Cell Cloning Method [PDF]
Cells, 2023 Mandarin fish ranavirus (MRV) infection poses a substantial challenge to the mandarin fish culture industry as no effective preventive or therapeutic measures currently exist.
Hetong Zhang +6 more
doaj +3 more sources
Peripheral B Lymphocyte Serves as a Reservoir for the Persistently Covert Infection of Mandarin Fish Siniperca chuatsi Ranavirus [PDF]
VirusesMandarin fish ranavirus (MRV) is a distinctive member among the genus Ranavirus of the family Iridoviridae. The persistently covert infection of MRV was previously observed in a natural outbreak of MRV, but the underlying mechanism remains unclear. Here,
Wenfeng Zhang +8 more
doaj +3 more sources
Rapid, sensitive, and visual detection of mandarin fish ranavirus and infectious spleen and kidney necrosis virus using an RPA-CRISPR/Cas12a system [PDF]
Frontiers in MicrobiologyIridoviruses are large cytoplasmic icosahedral viruses that contain dsDNA. Among them, mandarin fish ranavirus (MRV) and infectious spleen and kidney necrosis virus (ISKNV) are particularly notable due to their high contagiousness and pathogenicity ...
Zhoutao Lu +6 more
doaj +4 more sources
Ring finger protein 5 mediates STING degradation through ubiquitinating K135 and K155 in a teleost fish [PDF]
Frontiers in ImmunologyStimulator of interferon genes (STING) is a key connector protein in interferon (IFN) signaling, crucial for IFN induction during the activation of antiviral innate immunity.
Xiaowei Qin +9 more
doaj +2 more sources
Limited cross-species virus transmission in a spatially restricted coral reef fish community [PDF]
, 2023 The Great Barrier Reef (GBR) - the largest coral reef ecosystem in the world - supports over 1,200 fish species with some of the highest population densities and diversities observed in vertebrates, offering a high potential for virus transmission among ...
Bellwood, David R. +6 more
core +1 more source
Fish Iridoviridae: infection, vaccination and immune response [PDF]
Each year, due to climate change, an increasing number of new pathogens are being discovered and studied, leading to an increase in the number of known diseases affecting various fish species in different regions of the world.
Borrego García, Juan José +4 more
core +1 more source
A droplet digital PCR method for the detection of scale drop disease virus in yellowfin seabream (Acanthopagrus latus) [PDF]
In this study, a ddPCR method for the detection of scale drop disease virus (SDDV) in yellowfin seabream (Acanthopagrus latus) was established based on Real-time fluorescence quantitative PCR detection methods and principles. The reaction conditions were
Bin Yin +6 more
core +1 more source