Results 81 to 90 of about 2,239,293 (272)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Design, Analysis, and Manufacturing of Diffractive Achromatic Optical Systems
MicromachinesThe increasing resolution requirements of imaging optical systems must be satisfied by expanding the aperture of the optical system according to Rayleigh’s criterion, and larger apertures of conventional refractive/reflective optics place a greater ...
Yidi Zheng +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Free-form catenary-inspired meta-couplers for ultra-high or broadband vertical coupling
NanophotonicsMetasurface-assisted waveguide couplers, or meta-couplers, innovatively link free-space optics with on-chip devices, offering flexibility for polarization and wavelength (de)multiplexing, mode-selective coupling, and guided mode manipulation.
Chen Tianqu +11 more
doaj +1 more source
MicromachinesMask optimization is a critical technique for enhancing imaging performance in digital micromirror device (DMD)-based maskless lithography. Conventional algorithms, however, often suffer from slow convergence and limited adaptability, particularly when ...
Zhiyong Chen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
An Empirical Study of the Manipulability of Single Transferable Voting [PDF]
, 2010 Voting is a simple mechanism to combine together the preferences of multiple agents. Agents may try to manipulate the result of voting by mis-reporting their preferences. One barrier that might exist to such manipulation is computational complexity.
Walsh, Toby
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Coordinated task manipulation by nonholonomic mobile robots [PDF]
, 2006 Coordinated task manipulation by a group of autonomous mobile robots has received signicant research effort in the last decade. Previous studies in the area revealed that one of the main problems in the area is to avoid the collisions of the robots with ...
Güleç, Nusrettin +2 more
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