Results 61 to 70 of about 2,254,479 (296)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Manipulating Biphotonic Qutrits [PDF]

Physical Review Letters, 2008
4 pages, 4 ...
Lanyon, BP, Langford, NK, Weinhold, TJ, O'Brien, JL, Resch, KJ, Gilchrist, A, White, AG   +6 more
openaire   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Influence of Lithography Process Parameters on Continuous Surface Diffractive Optical Elements for Laser Beam Shaping

Micromachines
To address the demand for laser beam-shaping techniques, we developed a one-step exposure process based on moving-mask lithography for the fabrication of a continuous-surface diffractive optical element (DOE) for laser beam shaping.
Wenjing Liu, Axiu Cao, Junbo Liu, Hui Pang, Qiling Deng, Jian Wang, Song Hu   +6 more
doaj   +1 more source

The Complexity of Online Manipulation of Sequential Elections [PDF]

, 2012
Most work on manipulation assumes that all preferences are known to the manipulators. However, in many settings elections are open and sequential, and manipulators may know the already cast votes but may not know the future votes.
Hemaspaandra, Edith, Hemaspaandra, Lane A., Rothe, Joerg   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Opto‐Thermal‐Tension Mediated Precision Large‐Scale Particle Manipulation and Flexible Patterning

Advanced Science
Large‐scale particle manipulation with single‐particle precision and further flexible patterning into functional structures is of huge potentials in many fields including bio‐optoelectronic sensing, colloidal lithography, and wearable devices.
Ziyi He, Jianyun Xiong, Yang Shi, Guoshuai Zhu, Xing Li, Ting Pan, Baojun Li, Hongbao Xin   +7 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Research progress on the microbial metabolism and transport of polyamines and their roles in animal gut homeostasis

Journal of Animal Science and Biotechnology
Polyamines (putrescine, spermidine, and spermine) are aliphatic compounds ubiquitous in prokaryotes and eukaryotes. Positively charged polyamines bind to negatively charged macromolecules, such as nucleic acids and acidic phospholipids, and are involved ...
Chong Zhang, Yongkang Zhen, Yunan Weng, Jiaqi Lin, Xinru Xu, Jianjun Ma, Yuhong Zhong, Mengzhi Wang   +7 more
doaj   +1 more source

Multiform Adaptive Robot Skill Learning from Humans

, 2017
Object manipulation is a basic element in everyday human lives. Robotic manipulation has progressed from maneuvering single-rigid-body objects with firm grasping to maneuvering soft objects and handling contact-rich actions.
Lawhorn, Raheem, Lu, Lu, Ouyang, Bo, Patil, Siddharth, Susanibar, Steve, Wang, Cong, Zhao, Leidi   +6 more
core   +1 more source