Results 51 to 60 of about 1,194,241 (312)

Light-controlled soft bio-microrobot

Light: Science & Applications
Micro/nanorobots hold exciting prospects for biomedical and even clinical applications due to their small size and high controllability. However, it is still a big challenge to maneuver micro/nanorobots into narrow spaces with high deformability and ...
Jianyun Xiong, Xing Li, Ziyi He, Yang Shi, Ting Pan, Guoshuai Zhu, Dengyun Lu, Hongbao Xin   +7 more
doaj   +1 more source

Feeling manipulated: cytomegalovirus immune manipulation [PDF]

Virology Journal, 2009
No one likes to feel like they have been manipulated, but in the case of cytomegalovirus (CMV) immune manipulation, we do not really have much choice. Whether you call it CMV immune modulation, manipulation, or evasion, the bottom line is that CMV alters the immune response in such a way to allow the establishment of latency with lifelong shedding ...
Sparer Tim E, Miller-Kittrell Mindy
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Plasma Figure Correction Method Based on Multiple Distributed Material Removal Functions

Micromachines, 2023
In the process of plasma figure correction for a quartz sub-mirror, the plasma parallel removal process and ink masking layer are combined for the first time.
Xiang Wu, Bin Fan, Qiang Xin, Qian Luo, Junming Shao, Guohan Gao, Peiqi Jiao   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Learning Complex Dexterous Manipulation with Deep Reinforcement Learning and Demonstrations [PDF]

Robotics: Science and Systems, 2017
Dexterous multi-fingered hands are extremely versatile and provide a generic way to perform multiple tasks in human-centric environments. However, effectively controlling them remains challenging due to their high dimensionality and large number of ...
A. Rajeswaran, Vikash Kumar, Abhishek Gupta, John Schulman, E. Todorov, S. Levine   +5 more
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Full-space inverse-designed meta-optics for complex vector field shaping of intracavity landscapes

Light: Science & Applications
The sophisticated shaping of electromagnetic field landscapes, both outside and inside optical cavities, has long been an important goal of optics and photonics, with broad applications in near-field imaging, lithography, and laser science.
Mingfeng Xu, Di Sang, Mingbo Pu, Ping Gao, Bowen Zhao, Yuhan Zheng, Qingji Zeng, Lianwei Chen, Fei Zhang, Yinghui Guo, Xiong Li, Xiaoliang Ma, Yunqi Fu, Xiangang Luo   +13 more
doaj   +1 more source

Manipulation by design [PDF]

Electronic Markets
AbstractHuman behaviour is affected by architecture, including how online user interfaces are designed. The purpose of this article is to provide insights into the regulation of behaviour modification by the design of choice architecture in light of the European Union data protection law (GDPR) and marketing law (UCPD). It has become popular to use the
openaire   +1 more source