Results 51 to 60 of about 1,091,426 (262)

A modular verification and validation framework for hybrid-capture next-generation sequencing HLA typing in clinical histocompatibility laboratories

Frontiers in Genetics
Hybrid-capture next-generation sequencing HLA workflows are increasingly used in clinical histocompatibility laboratories for high-resolution HLA typing.
Alice Scarpa, Diego Ferrarese, Samantha Guidotti, Veronica Scaglia, Angela Rossi   +4 more
doaj   +1 more source

Grasp Point Optimization for Unknown Object Manipulation in Hand Task [PDF]

, 2012
Li Q, Haschke R, Bolder B, Ritter H. Grasp Point Optimization for Unknown Object Manipulation in Hand Task.
Bolder, Bram, Ritter, Helge ; https://orcid.org/, Haschke, Robert ; https://orcid.org/, Li, Qiang ; https://orcid.org/   +3 more
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Longitudinally continuous varying high-order cylindrical vector fields enabled by spin-decoupled metasurfaces

Nanophotonics
The manipulation of vector optical fields in three-dimensional (3D) space plays a vital role in both fundamental research and practical implementations of polarization optics.
He Xinye, Bao Hanlin, Zhang Fei, Kang Tongtong, Pu Mingbo, Chen Yan, Guo Yinghui, Gong Jintao, Xu Mingfeng, Luo Xiangang   +9 more
doaj   +1 more source

Two-fingered, tactile-based manipulation of unknown objects [PDF]

, 2013
Li Q, Haschke R, Ritter H. Two-fingered, tactile-based manipulation of unknown objects.
Ritter, Helge ; https://orcid.org/, Haschke, Robert ; https://orcid.org/, Li, Qiang ; https://orcid.org/   +2 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Dynamic nonlocal metasurface for multifunctional integration via phase-change materials

Nanophotonics
Non-local metasurface supporting geometric phases at bound states in the continuum (BIC) simultaneously enables sharp spectral resonances and spatial wavefront shaping, thus providing a diversified optical platform for multifunctional devices. However, a
Yu Shilin, Xu Mingfeng, Pu Mingbo, Tang Xi, Zheng Yuhan, Guo Yinghui, Zhang Fei, Li Xiong, Ma Xiaoliang, Luo Xiangang   +9 more
doaj   +1 more source

Non-Line-of-Sight Target Tracking With a Single Time Multiplexed Channel

IEEE Photonics Journal
Here we propose a non-line-of-sight (NLOS) tracking scheme using only one single-pixel single-photon channel. It is demonstrated that sending multiple beams with proper time delay enables multiplexing of multi-echoes of the hidden object in the single ...
Xianmin Zheng, Tailin Li, Ke Ding, Yihan Luo   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source