Results 51 to 60 of about 1,069,438 (262)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Full-space inverse-designed meta-optics for complex vector field shaping of intracavity landscapes
Light: Science & ApplicationsThe sophisticated shaping of electromagnetic field landscapes, both outside and inside optical cavities, has long been an important goal of optics and photonics, with broad applications in near-field imaging, lithography, and laser science.
Mingfeng Xu +13 more
doaj +1 more source
Plasma Figure Correction Method Based on Multiple Distributed Material Removal Functions
Micromachines, 2023 In the process of plasma figure correction for a quartz sub-mirror, the plasma parallel removal process and ink masking layer are combined for the first time.
Xiang Wu +6 more
doaj +1 more source
Simulation Results for Manipulation of Unknown Objects in Hand [PDF]
, 2011 Li Q, Haschke R, Ritter H, Bolder B. Simulation Results for Manipulation of Unknown Objects in Hand. In: Proc. ROBIO. 2011.In this paper, the authors proposed a novel reactive strategy to solve a unknown object local manipulation problem with an ...
Bolder, Bram +3 more
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Toward Autonoumous Visual-tactile Exploration and Manipulation [PDF]
, 2013 Li Q, Haschke R, Ritter H. Toward Autonoumous Visual-tactile Exploration and Manipulation.
Ritter, Helge ; https://orcid.org/ +2 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
IEEE Photonics Journal, 2014 A fiber Fabry-Perot interferometer (FPI) based on a bubble-expanded microcavity is investigated in this paper. Due to the expanded bubble microcavity, the FPI exhibits high strain sensitivity of 30.66 pm/με.
Chenchen Yin +8 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source