Results 91 to 100 of about 136,556 (304)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Configuration Design for 6-DOF Master Manipulator and Research on Spatial Trajectory Planning Simulation

open access: yesJixie chuandong, 2021
The master manipulator is an important part for minimally invasive surgical (MIS)robot. It is used to receive the doctor action and control the slave operator to complete the surgical operation.
Qingyun Wang   +4 more
doaj  

Fuzzy logic control of telerobot manipulators [PDF]

open access: yes
Telerobot systems for advanced applications will require manipulators with redundant 'degrees of freedom' (DOF) that are capable of adapting manipulator configurations to avoid obstacles while achieving the user specified goal.
Franke, Ernest A., Nedungadi, Ashok
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Mathematical Modeling of Forwarder Operation When Collecting Logs in the Forest Swath

open access: yesTehnički Glasnik
Optimization of the machines allows you to increase their productivity and reduce the labor costs for performing individual elements of the technological cycle of their work in the forest.
Konstantin P. Rukomojnikov   +2 more
doaj   +1 more source

Kinematics and Workspace Analysis of an 8-DOF Space Manipulator

open access: yesJixie chuandong, 2021
An 8-DOF manipulator with prismatic pair is proposed for space environment, which can complete equipment maintenance and object grabbing in space environment. The pose transformation matrix and forward kinematics equation of 8-DOF manipulator are derived
Kai Yang, Jinying Huang
doaj  

Model evaluation, recommendation and prioritizing of future work for the manipulator emulator testbed [PDF]

open access: yes
The Manipulator Emulator Testbed (MET) is to provide a facility capable of hosting the simulation of various manipulator configurations to support concept studies, evaluation, and other engineering development activities.
Kelly, Frederick A.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Two measures of performance in a peg-in-hole manipulation task with force feedback [PDF]

open access: yes
The results are described from two manipulators on a peg-in-hole task, which is part of a continued effort to develop models for human performance with remote manipulators. Task difficulty is varied by changing the diameter of the peg to be inserted in a
Hill, J. W.
core   +1 more source

Research issues in implementing remote presence in teleoperator control [PDF]

open access: yes, 1981
The concept of remote presence in telemanipulation is presented. A conceptual design of a prototype teleoperator system incorporating remote presence is described. The design is presented in functional terms, sensor, display, and control subsystem.
Corker, K., Lyman, J., Mishkin, A. H.
core   +1 more source

Home - About - Disclaimer - Privacy