Results 131 to 140 of about 44,027 (268)

Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]

open access: yes, 2015
Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K.   +10 more
core   +1 more source

The Life of a Kidney Podocyte

open access: yesActa Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth   +2 more
wiley   +1 more source

MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors. [PDF]

open access: yes, 2016
It had been thought that complement factor D (FD) is activated at the site of synthesis, and only FD lacking a propeptide is present in blood. The serum of mannose-binding lectin-associated serine protease (MASP)-1/3(-/-) mice contains pro-FD and has ...
Andrea Kocsis   +10 more
core   +1 more source

Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration

open access: yesScientific Reports, 2016
Age-related macular degeneration (AMD) is a major cause of severe, progressive visual loss among the elderly. There are currently no established serological markers for the diagnosis of AMD.
Hye-Jung Kim   +11 more
semanticscholar   +1 more source

Mannan-binding lectin is a determinant of survival in infective endocarditis

open access: yesClinical and Experimental Immunology, 2007
Summary Mannan-binding lectin (MBL) is a collectin plasma protein activating the lectin pathway of the complement system, enhancing opsonophagocytosis and modulating the cytokine response to inflammation. Deficiency of MBL, caused by structural mutations or promoter polymorphisms in the MBL2 gene, has been associated with increased ...
Tran, C.T.   +5 more
openaire   +4 more sources

A Modular Solid Phase Synthesis Approach for Glycocalix[4]Arene Derivatives and Their Multivalent Presentation on Ultrasmall Gold Nanoparticles.

open access: yesChemistry – A European Journal, Volume 31, Issue 40, July 17, 2025.
In this study, we present a calix[4]arene building block suitable for modular solid‐phase polymer synthesis and the preparation of functional glycocalix[4]arene. This allows us to incorporate carbohydrate ligands and further functionalities, such as alkynes at a specific position at the upper or lower rim of the calix[4]arene as demonstrated for the ...
Alisa Kayser   +8 more
wiley   +1 more source

Pattern recognition receptors in antifungal immunity [PDF]

open access: yes, 2014
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D   +2 more
core   +2 more sources

Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer

open access: yesSwiss Medical Weekly, 2011
QUESTIONS UNDER STUDY: Mannan-binding lectin (MBL) and MBL-associated serine protease-2 (MASP-2) are two key components of the lectin-pathway of complement-activation. Information on the potential role of lectin-pathway components in carcinogenesis
UP Fisch   +6 more
doaj   +1 more source

Innate immunity and neuroinflammation [PDF]

open access: yes, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Simultaneous activation of complement and coagulation by MBL-associated serine protease 2.

open access: yesPLoS ONE, 2007
The complement system is an important immune mechanism mediating both recognition and elimination of foreign bodies. The lectin pathway is one pathway of three by which the complement system is activated.
Anders Krarup   +4 more
doaj   +1 more source

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