Results 131 to 140 of about 44,027 (268)
Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]
Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K. +10 more
core +1 more source
ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source
MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors. [PDF]
It had been thought that complement factor D (FD) is activated at the site of synthesis, and only FD lacking a propeptide is present in blood. The serum of mannose-binding lectin-associated serine protease (MASP)-1/3(-/-) mice contains pro-FD and has ...
Andrea Kocsis +10 more
core +1 more source
Age-related macular degeneration (AMD) is a major cause of severe, progressive visual loss among the elderly. There are currently no established serological markers for the diagnosis of AMD.
Hye-Jung Kim +11 more
semanticscholar +1 more source
Mannan-binding lectin is a determinant of survival in infective endocarditis
Summary Mannan-binding lectin (MBL) is a collectin plasma protein activating the lectin pathway of the complement system, enhancing opsonophagocytosis and modulating the cytokine response to inflammation. Deficiency of MBL, caused by structural mutations or promoter polymorphisms in the MBL2 gene, has been associated with increased ...
Tran, C.T. +5 more
openaire +4 more sources
In this study, we present a calix[4]arene building block suitable for modular solid‐phase polymer synthesis and the preparation of functional glycocalix[4]arene. This allows us to incorporate carbohydrate ligands and further functionalities, such as alkynes at a specific position at the upper or lower rim of the calix[4]arene as demonstrated for the ...
Alisa Kayser +8 more
wiley +1 more source
Pattern recognition receptors in antifungal immunity [PDF]
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D +2 more
core +2 more sources
Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer
QUESTIONS UNDER STUDY: Mannan-binding lectin (MBL) and MBL-associated serine protease-2 (MASP-2) are two key components of the lectin-pathway of complement-activation. Information on the potential role of lectin-pathway components in carcinogenesis
UP Fisch +6 more
doaj +1 more source
Innate immunity and neuroinflammation [PDF]
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core +3 more sources
Simultaneous activation of complement and coagulation by MBL-associated serine protease 2.
The complement system is an important immune mechanism mediating both recognition and elimination of foreign bodies. The lectin pathway is one pathway of three by which the complement system is activated.
Anders Krarup +4 more
doaj +1 more source

