Results 221 to 230 of about 14,274 (254)

Mannan-binding protein, a complement activating animal lectin

Immunopharmacology, 1992
Mannan-binding protein is an animal serum lectin (i.e. a molecule with the ability to bind specifically to certain carbohydrate structures). The relevant carbohydrate ligands are found on many pathogenic microorganisms. After binding to suitable carbohydrate ligands, mannan-binding protein is found to be an activator of the classical pathway of ...
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Phospholipid-binding activity of human mannan-binding lectin

Immunology Letters, 1998
Some C-type lectins possess phospholipid-binding ability, which may be of physiological importance. Human mannan-binding lectin (MBL) was found to bind specifically to solid-phase phosphatidylserine (PS), phosphatidylinositol (PI) and phosphatidylcholine (PC), but not cardiolipin (CL), in a concentration-dependent manner. This property was inhibited by
openaire   +2 more sources

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Signal Transduction and Targeted Therapy, 2022
Lin Zhu, Shoudeng Chen, Xiu-Wu Bian
exaly  

Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

Nature Immunology, 2021
Santiago P Méndez-Huergo, Chengliang Wang, Margaret M Fettis   +2 more
exaly  

Mannan-Binding Lectin Polymorphisms and Infectious Diseases

2008
Møller-Kristensen, Mette, Thiel, Steffen, Jensenius, Jens Christian   +2 more
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P1752 Mannan-binding lectin in neonates

International Journal of Antimicrobial Agents, 2007
A. Szala, S. MacDonald, I. Domzalska-Popadiuk, A. Atkinson, M. Cedzynski, A. Swierzko, J. Szemraj, M. Borkowska, J. Szczapa, M. Matsushita, M. Turner, D. Kilpatrick   +11 more
openaire   +1 more source

Mannan-binding lectin activates C3 and the

2006
Lectin pathway activation of C3 is known to involve target recognition by mannan-binding lectin (MBL) or ficolins and generation of classical pathway C3 convertase via cleavage of C4 and C2 by MBL-associated serine protease 2 (MASP-2). We investigated C3 activation in C2-deficient human sera and in sera with other defined defects of complement to ...
Selander, B., Martensson, U., Weintraub, A., Holmstrom, E., Matsushita, M., Thiel, Steffen, Jensenius, Jens Christian, Truedsson, L., Sjoholm, A.G.   +8 more
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Signalling through C-type lectin receptors: shaping immune responses

Nature Reviews Immunology, 2009
Teunis B H Geijtenbeek
exaly  

C-type lectin receptors on dendritic cells and langerhans cells

Nature Reviews Immunology, 2002
Carl Figdor
exaly  

C-type lectin receptors in the control of T helper cell differentiation

Nature Reviews Immunology, 2016
Teunis B H Geijtenbeek
exaly