Results 81 to 90 of about 14,274 (254)
Mannan-Binding Lectin Serum Levels in 593 Healthy Iranian Children and Adults
Iranian Journal of Allergy, Asthma and Immunology, 2014 Mannan-binding lectin (MBL) is a vital protein of innate immune system and has two critical functions: complement activation through the lectin pathway and opsonization.
Sara Zahedifard +8 more
doaj
MASP-1 induces a unique cytokine pattern in endothelial cells: a novel link between complement system and neutrophil granulocytes. [PDF]
PLoS ONE, 2014 Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this immediate anti-microbial action.
Péter K Jani +10 more
doaj +1 more source
Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri +5 more
wiley +1 more source
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
Immunology, Volume 177, Issue 2, Page 254-269, February 2026.We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Covalent Activation of the C‐type Lectin DC‐SIGN
Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.We introduce the first covalent activators of a C‐type lectin. Using orthogonal functional assays, NMR, MS/MS, and computational modeling, we delineate mechanisms from a functional electrophile‐first screen on dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing non‐integrin (DC‐SIGN) that yields two modes: N‐hydroxysuccinimide (NHS ...
Jonathan Lefèbre +9 more
wiley +1 more source
Applications of mannose-binding lectins and mannan glycoconjugates in nanomedicine [PDF]
, 2022 Anita Gupta, Anita Gupta
openalex +1 more source
Mannan-binding lectin concentration during normal human pregnancy [PDF]
Human Reproduction, 2000 Relative deficiency of mannan-binding lectin (MBL) is associated with recurrent miscarriage. To investigate whether MBL concentration alters as a result of pregnancy, serial measurements were made in 14 patients before and during normal early pregnancy.
openaire +2 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Scabies mite peritrophins are potential targets of human host innate immunity. [PDF]
PLoS Neglected Tropical Diseases, 2011 BACKGROUND: Pruritic scabies lesions caused by Sarcoptes scabiei burrowing in the stratum corneum of human skin facilitate opportunistic bacterial infections.
Angela Mika +4 more
doaj +1 more source
Immunity against fungal beta 1,3 glucan carbohydrate in the gastrointestinal tract [PDF]
, 2016 Inflammatory Bowel Disease (IBD) is a debilitating, life- long disease that affects about 1.4 millions Americans. Little is known about the pathogenesis of IBD and an effective cure still remains to be discovered.
Feliu, Marianela
core +1 more source