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An overview of mannan structure and mannan-degrading enzyme systems

Applied Microbiology and Biotechnology, 2008
Hemicellulose is a complex group of heterogeneous polymers and represents one of the major sources of renewable organic matter. Mannan is one of the major constituent groups of hemicellulose in the wall of higher plants. It comprises linear or branched polymers derived from sugars such as D-mannose, D-galactose, and D-glucose.
L R S, Moreira, E X F, Filho
exaly   +3 more sources

Biosynthesis of yeast mannan. Characterization of mannan-synthesizing enzyme systems from mutants defective in mannan structure

Folia Microbiologica, 1976
The yeast Saccharomyces cerevisiae X2180-1A (wild) and its mutants X2180-1A-4 (mnn 1) and X2180-1A-5 (mnn 2) defective in mannan biosynthesis were used as enzyme sources to catalyze in vitro mannosyl transfer from GDP-[14C-U]-mannose to endogenous glycoproteins as well as to exogenous, low-molecular weight acceptors.
V, Farkas, S, Bauer
openaire   +2 more sources

Antioxidant and antimutagenic activity of mannan neoglycoconjugates: Mannan–human serum albumine and mannan–penicillin G acylase

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2006
The antioxidant and antimutagenic activity of the yeast cell-wall mannan and mannan conjugates--in particular the mannan of Saccharomyces cerevisiae (M-S.c.) and conjugates of mannan S. cerevisiae with human serum albumin (M-HSA1, M-HSA2) and the microbial enzyme penicillin G acylase (M-PGA)--were evaluated in vitro in the unicellular flagellate ...
Lívia, Krizková   +6 more
openaire   +2 more sources

Immunostimulatory properties of coffee mannans

Molecular Nutrition & Food Research, 2009
AbstractCoffee infusion mannans are acetylated polysaccharides containing single Galp and Araf residues as side chains of a β‐(1 → 4)‐Manp backbone. These mannans are structurally similar to the bioactive acetylated mannans from Aloe vera (AV). In this study, acetylated mannans were obtained from two coffee infusions prepared from light and dark ...
Joana, Simões   +5 more
openaire   +2 more sources

Mannosylphosphate transfer to yeast mannan

Biochimica et Biophysica Acta (BBA) - General Subjects, 1999
Mannoproteins located in the outermost layer of yeast cell wall determine the wall's porosity and thereby regulate leakage of proteins from the periplasmic space and entrance of macromolecules from the environment. In several yeasts, including Saccharomyces cerevisiae, the glycan portion of mannoproteins is composed not only of neutral oligosaccharides
Y, Jigami, T, Odani
openaire   +2 more sources

A procoagulant chemically sulfated mannan

Carbohydrate Polymers, 2016
Disorders of hemostasis can produce innumerous problems. Polysaccharides have been studied both as anticoagulant and as procoagulant agents. A mannan with a main chain of α-(1 → 6)-linked-Manp units, branched at O-2 mainly by side-chains of 2-O-linked-α-Manp units was chemically sulfated, structurally characterized by NMR and GC-MS (methylation ...
Ana Helena P, Gracher   +3 more
openaire   +2 more sources

Mannan-binding lectin in malignancy

Molecular Immunology, 2013
Complement may play a dual role in cancer: it may contribute either to the development or to the inhibition of tumour growth. Its components may be candidate biomarkers facilitating the disease detection, its progress or effectiveness of therapy. Additionally, complement deficiencies may increase the risk of infections and contribute to the higher ...
Anna S, Swierzko   +2 more
openaire   +2 more sources

Quantification of mannan-binding lectin

Journal of Immunological Methods, 2006
Mannan-binding lectin (MBL) is attracting considerable interest due to its role in the immune defense. The high frequency of congenital MBL deficiency makes it feasible to evaluate clinical relevance through epidemiological investigations on fairly limited numbers of patients.
Frederiksen, Pernille D   +5 more
openaire   +3 more sources

Introduction to mannan-binding lectin

Biochemical Society Transactions, 2003
Mannan-binding lectin (MBL) was first discovered as a plasma opsonin for baker's yeast and was independently characterized biochemically. It belongs to the small subfamily of collectins: C-type lectins possessing a collagen-like domain. MBL is synthesized by the liver and secreted into the bloodstream.
openaire   +2 more sources

Mannan-Binding Lectin and Mannan-Binding Lectin-Associated Serine Protease 2 in Acute Pancreatitis

Pancreas, 2011
Complement activation may play a prominent role in acute pancreatitis (AP). Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) participate in complement activation. The objective of the present study was to evaluate the role of MBL and MASP-2 as markers in AP with regard to etiology, inflammatory activity, severity, and ...
Novovic, Srdan   +6 more
openaire   +5 more sources

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