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Mannan-binding lectin in malignancy

Molecular Immunology, 2013
Complement may play a dual role in cancer: it may contribute either to the development or to the inhibition of tumour growth. Its components may be candidate biomarkers facilitating the disease detection, its progress or effectiveness of therapy. Additionally, complement deficiencies may increase the risk of infections and contribute to the higher ...
Anna S, Swierzko   +2 more
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Quantification of mannan-binding lectin

Journal of Immunological Methods, 2006
Mannan-binding lectin (MBL) is attracting considerable interest due to its role in the immune defense. The high frequency of congenital MBL deficiency makes it feasible to evaluate clinical relevance through epidemiological investigations on fairly limited numbers of patients.
Frederiksen, Pernille D   +5 more
openaire   +3 more sources

Introduction to mannan-binding lectin

Biochemical Society Transactions, 2003
Mannan-binding lectin (MBL) was first discovered as a plasma opsonin for baker's yeast and was independently characterized biochemically. It belongs to the small subfamily of collectins: C-type lectins possessing a collagen-like domain. MBL is synthesized by the liver and secreted into the bloodstream.
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Mannan-Binding Lectin and Mannan-Binding Lectin-Associated Serine Protease 2 in Acute Pancreatitis

Pancreas, 2011
Complement activation may play a prominent role in acute pancreatitis (AP). Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) participate in complement activation. The objective of the present study was to evaluate the role of MBL and MASP-2 as markers in AP with regard to etiology, inflammatory activity, severity, and ...
Novovic, Srdan   +6 more
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Alkaline Degradation of Mannan

Holzforschung, 1986
Etude par GLC capillaire-spectroscopie de masse des acides carboxyliques formes lors d'un traitement alcalin du mannane et du ...
Klaus Niemelä, Eero Sjöström
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Mannan binding lectin and viral hepatitis

Immunology Letters, 2007
Mannan binding lectin (MBL) is a pattern recognition molecule of the innate immune system that binds to sugars on the surface of invading micro-organisms. Target binding, complement activation and other functions of MBL are dependent on the presence of multiple carbohydrate recognition domains.
Kristelle S, Brown   +4 more
openaire   +2 more sources

Synthesis of a Candida albicans tetrasaccharide spanning the β1,2-mannan phosphodiester α-mannan junction

Organic & Biomolecular Chemistry, 2012
The cell wall phosphomannan of Candida species is a complex N-linked glycoprotein with a glycan chain containing predominantly an α-linked mannose backbone with α-mannose branches. A minor β-mannan component is attached to the branches either via a glycosidic bond (acid stable β-mannan) or a phosphodiester bond (acid-labile β-mannan).
Anh-Thu, Dang   +2 more
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Biosynthesis of salep mannan

Phytochemistry, 1973
A particulate enzyme system, isolated from growing orchid tubers (Orchis morio), was shown to catalyse the transfer of mannose from guanosine-diphosphate-mannose-14C and its incorporation into alkali-insoluble mannan with the same type of linkage [β(1 → 4)-d-mannopyranosyl] as is contained in the naturally-occurring reserve polysaccharide.
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Immunochemistry of Candida Mannans

1991
The first description on the serological heterogeneity in C. albicans was published by Hasenclever and Mitchell (1961). These workers revealed that this species could be classified into two serotypes, A and B, as judged from the results of agglutination assay between the cells of large number of C.
S. Suzuki, N. Shibata, H. Kobayashi
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RECOMBINANT HUMAN MANNAN-BINDING LECTIN

1999
The present invention relates to methods of producing and/or isolating MEL compositions. In particular the inven­tion relates to methods of producing and/or isolating novel recombinant human MEL preparations with high similarity to natural human MEL.
Vorup-Jensen, Thomas   +2 more
openaire   +2 more sources

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