Results 41 to 50 of about 24,247 (244)

The Use of Electrochemical Voltammetric Techniques and High-Pressure Liquid Chromatography to Evaluate Conjugation Efficiency of Multiple Sclerosis Peptide-Carrier Conjugates

Brain Sciences, 2020
Recent studies have shown the ability of electrochemical methods to sense and determine, even at very low concentrations, the presence and quantity of molecules or analytes including pharmaceutical samples.
Efstathios Deskoulidis, Sousana Petrouli, Vasso Apostolopoulos, John Matsoukas, Emmanuel Topoglidis   +4 more
doaj   +1 more source

Myelin Peptide–Mannan Conjugate Multiple Sclerosis Vaccines: Conjugation Efficacy and Stability of Vaccine Ingredient

Vaccines, 2021
Myelin peptide–mannan conjugates have been shown to be potential vaccines in the immunotherapy of multiple sclerosis. The conjugates are comprised from the epitope peptide and the polysaccharide mannan which transfers as a carrier the antigenic peptide ...
John Matsoukas, George Deraos, Kostas Kelaidonis, Md Kamal Hossain, Jack Feehan, Andreas G. Tzakos, Elizabeth Matsoukas, Emmanuel Topoglidis, Vasso Apostolopoulos   +8 more
doaj   +1 more source

Mannan-Abeta₂₈ conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Journal of Neuroinflammation, 2008
Background New pre-clinical trials in AD mouse models may help to develop novel immunogen-adjuvant configurations with the potential to avoid the adverse responses that occurred during the clinical trials with AN-1792 vaccine formulation.
Karapetyan Adrine, Vasilevko Vitaly, Ajdari Rodmehr, Movsesyan Nina, Mamikonyan Grigor, Mkrtichyan Mikayel, Ghochikyan Anahit, Petrushina Irina, Lees Andrew, Agadjanyan Michael G, Cribbs David H   +10 more
doaj   +1 more source

Stimulation of Interferon Production by Mannans

Experimental Biology and Medicine, 1970
SummaryFour preparations of purified mannans from C. albicans Berkhout, one purified mannan from S. cerevisiae, a lipid fraction from C. albicans Berkhout, and eight polysaccharide-protein complexes from the same microorganism were tested for interferon-stimulating activity in explanted mouse peritoneal leukocytes. Whereas the mannan from S. cerevisiae
Dobroslav Sikl, Ladislav Masler, Ladislav Borecky, Š. Bauer, Vladimir Lackovic   +4 more
openaire   +3 more sources

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Mannan endo-1,4-β-mannosidase from Kitasatospora sp. isolated in Indonesia and its potential for production of mannooligosaccharides from mannan polymers

AMB Express, 2017
Mannan endo-1,4-β-mannosidase (commonly known as β-mannanase) catalyzes a random cleavage of the β-d-1,4-mannopyranosyl linkage in mannan polymers. The enzyme has been utilized in biofuel production from lignocellulose biomass, as well as in production ...
Nanik Rahmani, Norimasa Kashiwagi, JaeMin Lee, Satoko Niimi-Nakamura, Hana Matsumoto, Prihardi Kahar, Puspita Lisdiyanti, Yopi, Bambang Prasetya, Chiaki Ogino, Akihiko Kondo   +10 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

On the utilization of salep mannan

Experimental Biology and Medicine, 1919
Some experiments on the utilization of salep mannan were reported in 1911.1 It was found that this anhydride of mannose was not hydrolyzed by the enzymes of saliva, pancreatic and intestinal juice, nor by malt diastase, but disappeared almost completely from the human alimentary tract when eaten, the coefficient of digestibility in three out of four ...
openaire   +2 more sources

Techno‐Economic Analysis of Polylactic Acid from Corn Stover: Understanding Uncertainty and Variability via Artificial Intelligence Tools

Advanced Sustainable Systems, EarlyView.
This study analyses the uncertainty and variability existing in the economic performance of polylactic acid (PLA) production, via integrating techno‐economic analysis with process models and Monte Carlo simulation enabled by artificial intelligence. The results show that the minimum selling price varies from $2,107 to $3076/t PLA.
Yinqiao Wang, Jiawei Huang, Chuan Xu, Sipan Liu, Junwei Li, Kai Lan   +5 more
wiley   +1 more source

SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B

Advanced Science, EarlyView.
We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang, Yuewei Zhan, Haonan Lin, Jiyang Chen, Mohamed N. Seleem, Michael Mansour, Ji‐Xin Cheng   +6 more
wiley   +1 more source