Results 41 to 50 of about 24,864 (245)

Mannan-Based Nanodiagnostic Agents for Targeting Sentinel Lymph Nodes and Tumors

Molecules, 2020
Early detection of metastasis is crucial for successful cancer treatment. Sentinel lymph node (SLN) biopsies are used to detect possible pathways of metastasis spread.
Markéta Jirátová, Andrea Gálisová, Maria Rabyk, Eva Sticová, Martin Hrubý, Daniel Jirák   +5 more
doaj   +1 more source

Favorable outcome of hepatosplenic candidiasis in a patient with acute leukemia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2015
Introduction. Acute leukemias treatment requires strong chemotherapy. Patients that develop bone marrow aplasia become immunocompromised, thus becoming liable to bacterial and fungal infections.
Čolović Nataša, Arsić-Arsenijević Valentina, Suvajdžić Nada, Đunić Irena, Tomin Dragica   +4 more
doaj   +1 more source

Mannan Enhances IL-12 Production by Increasing Bacterial Uptake and Endosomal Degradation in L. acidophilus and S. aureus Stimulated Dendritic Cells

Frontiers in Immunology, 2019
The mannose receptor (MR) is a C-type lectin involved in endocytosis and with a poorly defined ability to modulate cellular activation. We investigated the effect of mannan treatment prior to stimulation of murine bone marrow-derived dendritic cells with
Ronja Mathiesen, Helene M. S. Eld, Juliane Sørensen, Eva Fuglsang, Lisbeth Drozd Lund, Valentina Taverniti, Valentina Taverniti, Hanne Frøkiær   +7 more
doaj   +1 more source

The Use of Electrochemical Voltammetric Techniques and High-Pressure Liquid Chromatography to Evaluate Conjugation Efficiency of Multiple Sclerosis Peptide-Carrier Conjugates

Brain Sciences, 2020
Recent studies have shown the ability of electrochemical methods to sense and determine, even at very low concentrations, the presence and quantity of molecules or analytes including pharmaceutical samples.
Efstathios Deskoulidis, Sousana Petrouli, Vasso Apostolopoulos, John Matsoukas, Emmanuel Topoglidis   +4 more
doaj   +1 more source

Encapsulation of Polyphenolic Compounds Based on Hemicelluloses to Enhance Treatment of Inflammatory Bowel Diseases and Colorectal Cancer

Molecules, 2023
Inflammatory bowel diseases (IBD) and colorectal cancer (CRC) are difficult to cure, and available treatment is associated with troubling side effects. In addition, current therapies have limited efficacy and are characterized by high costs, and a large ...
Miłosz Caban, Urszula Lewandowska
doaj   +1 more source

Mannan oligosaccharide requires functional ETC and TLR for biological radiation protection to normal cells

BMC Cell Biology, 2018
Background Low LET Ionizing radiation is known to alter intracellular redox balance by inducing free radical generation, which may cause oxidative modification of various cellular biomolecules. The extent of biomolecule-modifications/ damages and changes
Sweta Sanguri, Damodar Gupta
doaj   +1 more source

Myelin Peptide–Mannan Conjugate Multiple Sclerosis Vaccines: Conjugation Efficacy and Stability of Vaccine Ingredient

Vaccines, 2021
Myelin peptide–mannan conjugates have been shown to be potential vaccines in the immunotherapy of multiple sclerosis. The conjugates are comprised from the epitope peptide and the polysaccharide mannan which transfers as a carrier the antigenic peptide ...
John Matsoukas, George Deraos, Kostas Kelaidonis, Md Kamal Hossain, Jack Feehan, Andreas G. Tzakos, Elizabeth Matsoukas, Emmanuel Topoglidis, Vasso Apostolopoulos   +8 more
doaj   +1 more source

Mannan-Abeta₂₈ conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Journal of Neuroinflammation, 2008
Background New pre-clinical trials in AD mouse models may help to develop novel immunogen-adjuvant configurations with the potential to avoid the adverse responses that occurred during the clinical trials with AN-1792 vaccine formulation.
Karapetyan Adrine, Vasilevko Vitaly, Ajdari Rodmehr, Movsesyan Nina, Mamikonyan Grigor, Mkrtichyan Mikayel, Ghochikyan Anahit, Petrushina Irina, Lees Andrew, Agadjanyan Michael G, Cribbs David H   +10 more
doaj   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Softening-up mannan-rich cell walls [PDF]

Journal of Experimental Botany, 2012
The softening and degradation of the cell wall (CW), often mannan enriched, is involved in several processes during development of higher plants, such as meristematic growth, fruit ripening, programmed cell death, and endosperm rupture upon germination. Mannans are also the predominant hemicellulosic CW polymers in many genera of green algae.
Rodriguez Gacio, Maria del Carmen, Iglesias Fernández, Raquel, Carbonero Zalduegui, Pilar, Matilla, Angel J.   +3 more
openaire   +3 more sources