Results 11 to 20 of about 152,345 (256)

The Fabrication, Drug Loading, and Release Behavior of Porous Mannitol

Molecules
Porous materials are widely used as an effective strategy for the solubilization of insoluble drugs. In order to improve the solubility and bioavailability of low water-solubility drugs, it is necessary to prepare porous materials. Mannitol is one of the
Zhe Li, Xiaosui Luo, Qiong Li, Zhengji Jin, Abid Naeem, Weifeng Zhu, Lihua Chen, Yi Feng, Liangshan Ming   +8 more
doaj   +2 more sources

Influence of Batch Cooling Crystallization on Mannitol Physical Properties and Drug Dispersion from Dry Powder Inhalers [PDF]

, 2012
This study provides, for the first time, an evaluation of the physicochemical properties of batch cooling crystallized mannitol particles combined with how these properties correlated with the inhalation performance from a dry powder inhaler (Aerolizer).
Hassan Larhrib (2076589), Waseem Kaialy (2076586), Ticehurst, Martyn, Larhrib, Hassan, Kaialy, Waseem, Ticehurst, Martyn D, Martyn Ticehurst (2076583), Nokhodchi, Ali, Larhrib, El Hassan, Ali Nokhodchi (4465915)   +9 more
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Urinary CC16 after challenge with dry air hyperpnoea and mannitol in recreational summer athletes [PDF]

, 2013
Airway epithelial injury is regarded as a key contributing factor to the pathogenesis of exercise-induced bronchoconstriction (EIB) in athletes. The concentration of the pneumoprotein club cell (Clara cell) CC16 in urine has been found to be a non ...
Pascale Kippelen, Leena Ali, Ali, Leena, Anderson, Sandra D., Bjermer, Leif, Tufvesson, E, Bjermer, L, Tufvesson, Ellen, Ali, L, Kippelen, P, Kippelen, Pascale, Leif Bjermer, Sandra D. Anderson, Anderson, SD, Ellen Tufvesson   +14 more
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Structure of the Cytoplasmic Loop between Putative Helices II and III of the Mannitol Permease of Escherichia coli: A Tryptophan and 5-Fluorotryptophan Spectroscopy Study [PDF]

, 2008
In this work, four single tryptophan (Trp) mutants of the dimeric mannitol transporter of Escherichia coli, EIImtl, are characterized using Trp and 5-fluoroTrp (5-FTrp) fluorescence spectroscopy.
Bokhove, Marcel,, Broos, Jaap,, Erwin P. P. Vos, Hesp, Ben H., Vos, Erwin P. P., Vos, Erwin P.P.,, Hesp, Ben H.,, Broos, Jaap, Bokhove, Marcel, Ben H. Hesp, Jaap Broos, Marcel Bokhove   +11 more
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The functional importance of structural differences between the mannitol-specific IIAmannitol and the regulatory IIAnitrogen [PDF]

, 1998
The three-dimensional structures of the IIA domain of the mannitol-specific phosphoenol-pyruvate dependent phosphotransferase system (PTS) of Escherichia coli and the regulatory IIAntr enzyme have been compared.
Dijkstra, BW, Van Montfort, RLM, Dijkstra, Bauke W., Montfort, Rob L.M. van,, Dijkstra, Bauke W.,, Montfort, Rob L.M. van   +5 more
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The role for osmotic agents in children with acute encephalopathies: a systematic review [PDF]

, 2010
Background: Raised intracranial pressure (ICP) is known to complicate both traumatic and non-traumatic encephalopathies. It impairs cerebral perfusion and may cause death due to global ischaemia and intracranial herniation. Osmotic agents are widely used
Idro, R, Gatakaa Hellen, Richard Idro, Gwer, S, Charles R Newton, Mwai, L, Leah Mwai, Newton Charles R, Samson Gwer, Gatakaa, H, Gwer Samson, Idro Richard, Newton, CR, Hellen Gatakaa, Mwai Leah   +14 more
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Characterization and Antibiofilm Activity of Mannitol–Chitosan-Blended Paste for Local Antibiotic Delivery System

Marine Drugs, 2019
Mannitol, a polyalcohol bacterial metabolite, has been shown to activate dormant persister cells within bacterial biofilm. This study sought to evaluate an injectable blend of mannitol, chitosan, and polyethylene glycol for delivery of antibiotics and ...
Leslie R. Pace, Zoe L. Harrison, Madison N. Brown, Warren O. Haggard, J. Amber Jennings   +4 more
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Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms. [PDF]

PLoS ONE, 2013
The failure of antibiotic therapies to clear Pseudomonas aeruginosa lung infection, the key mortality factor for cystic fibrosis (CF) patients, is partly attributed to the high tolerance of P. aeruginosa biofilms.
Nicolas Barraud, Alberto Buson, Wolfgang Jarolimek, Scott A Rice   +3 more
doaj   +1 more source

Mannitol at clinical concentrations activates multiple signaling pathways and induces apoptosis in endothelial cells [PDF]

, 1998
Background and Purpose—Hyperosmotic mannitol therapy is widely used in the clinical setting for acute and subacute reduction in brain edema, to decrease muscle damage in compartment syndrome, and to improve renal perfusion.
Malek, A.M., Jiang, L., Izumo, S., Vandorpe, D.H., Alper, S.L., Goss, G.G.   +5 more
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Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]

, 2010
An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Schepens, M.A.A., Schepens, Marloes A. A.,, Bovee-Oudenhoven, I.M.J., Brummer, R.J.M., Willemsen, Linette E. M.,, Rijnierse, A., Bovee-Oudenhoven, Ingeborg M. J.,, Schonewille, A.J., Vink, C., Arjan J. Schonewille, Rijnierse, Anneke,, Willemsen, L.E.M., Anneke Rijnierse, Carolien Vink, Marloes A. A. Schepens, Meer, R., van de, Willemsen, L. E., Linette E. M. Willemsen, Vink, Carolien,, Bovee Oudenhoven, I.M., Brummer, R.J., Brummer, Robert,, Roelof van der Meer, van der Meer, Roelof,, van der Meer, R., Ingeborg M. J. Bovee-Oudenhoven, van de Meer, R., Robert-Jan M. Brummer, Schonewille, Arjan J.,   +28 more
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