Results 11 to 20 of about 127,314 (247)
Safety and Tolerability, Dose-Escalating, Double-Blind Trial of Oral Mannitol in Parkinson's Disease
Frontiers in Neurology, 2022 Mannitol, a natural alcoholic-sugar, was recently suggested as a potential disease-modifying agent in Parkinson's disease. In animal models of the disease, mannitol interferes with the formation of α-synuclein fibrils, inhibits the formation of α ...
Eduard Linetsky +8 more
doaj +1 more source
Association between Renal Failure and Mannitol among Patients Who Have Acute Cerebral Infarction with Cerebral Edema [PDF]
Journal of Neurocritical Care, 2016 Background Renal failure is one of the most common side effects of mannitol. However, very little is known regarding the cause, incidence, risk factors, and outcome of mannitol-induced renal failure.
In Sung Choo +5 more
doaj +1 more source
Fermentation of Mannitol Extracts From Brown Macro Algae by Thermophilic Clostridia
Frontiers in Microbiology, 2018 Mannitol-containing macro algae biomass, such as Ascophyllum nodosum and Laminaria digitata, are a potential feedstock for the production of biofuels such as bioethanol.
Theo Chades +3 more
doaj +1 more source
Experimental Biology and Medicine, 1954 SummaryRadioactive mannitol has been administered to rats with the following results: 1. When given orally, about 50% of the mannitol carbon is recovered in the expired CO2 in 12 hours. 2. With intraperitoneal injection, the mannitol is largely recovered in urine with only 2-3% of the mannitol carbon recovered in the expired CO2. 3.
A N, WICK, T N, MORITA, L, JOSEPH
openaire +2 more sources
Marine Drugs, 2019 Mannitol, a polyalcohol bacterial metabolite, has been shown to activate dormant persister cells within bacterial biofilm. This study sought to evaluate an injectable blend of mannitol, chitosan, and polyethylene glycol for delivery of antibiotics and ...
Leslie R. Pace +4 more
doaj +1 more source
Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms. [PDF]
PLoS ONE, 2013 The failure of antibiotic therapies to clear Pseudomonas aeruginosa lung infection, the key mortality factor for cystic fibrosis (CF) patients, is partly attributed to the high tolerance of P. aeruginosa biofilms.
Nicolas Barraud +3 more
doaj +1 more source
Diurnal Regulation of Leaf Water Status in High- and Low-Mannitol Olive Cultivars
Plants, 2014 The role of mannitol and malic acid in the regulation of diurnal leaf water relations was investigated in ‘Biancolilla’ (high-mannitol) and ‘Cerasuola’ (low-mannitol) olive trees.
Riccardo Lo Bianco, Giuseppe Avellone
doaj +1 more source
Synthesis of some novel sulfonyl ester derivatives derived from d-mannitol
Journal of Saudi Chemical Society, 2010 The preparation of sulfonate-derivatives of d-mannitol i.e. 1,2:3,4-di-O-isopropylidene-3,4-di-O-p-toluenesulfonate-d-mannitol (3a), 1,2:3,4-di-O-isopropylidene-3,4-di-O-methanesulfonate-d-mannitol (3b), and 1, 2:3,4-di-O-isopropylidene-3,4-di-O ...
Abdullah M. Al Majid
doaj +1 more source
The Nephroprotective Effect of Mannitol in Head and Neck Cancer Patients Receiving Cisplatin Therapy
Clinical Medicine Insights: Oncology, 2019 Introduction: Cisplatin is used as treatment for several different malignancies and a well-known complication is irreversible kidney damage. To protect the kidneys, this treatment is often combined with mannitol infusion to promote osmotic diuresis ...
Erik Hägerström +5 more
doaj +1 more source
Pharmacokinetics of oral mannitol for bowel preparation for colonoscopy
Clinical and Translational Science, 2022 This study aimed to define the pharmacokinetics (PKs) of oral mannitol used as an osmotic laxative for bowel preparation for colonoscopy. The PKs of oral mannitol was evaluated in a substudy as part of a phase II dose‐finding, international, multicenter,
Giancarla Fiori +16 more
doaj +1 more source