Results 31 to 40 of about 127,571 (248)

Inducible Mtld expression facilitated the introduction of the mannitol synthesis pathway in Synechococcus elongatus PCC 7942

open access: yesFrontiers in Bioengineering and Biotechnology
Mannitol is a valuable sugar alcohol, extensively used across various industries. Cyanobacteria show potential as future platforms for mannitol production, utilizing CO2 and solar energy directly. The proof-of-concept has been demonstrated by introducing
Jiahui Sun   +36 more
doaj   +1 more source

Effect of mannitol on cerebrovascular pressure reactivity in patients with intracranial hypertension

open access: yesJournal of the Formosan Medical Association, 2015
Mannitol is commonly used in patients with increased intracranial pressure (ICP), but its effect on cerebrovascular pressure reactivity (CVPR) is uncertain.
Sung-Chun Tang   +6 more
doaj   +1 more source

Effect of mannitol injection rate on intracranial pressure (甘露醇静脉推注速度对颅内压的影响)

open access: yes中西医结合护理, 2021
Objective To investigate the effect of static pushing speed of mannitol on the intracranial pressure. Methods Totally 70 children with acute intracranial pressure increase were divided into two groups: 35 cases in the control group received routine ...
ZHUANGLI Jingyi (庄丽静怡)   +1 more
doaj   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

open access: yesAdvanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà   +15 more
wiley   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

open access: yesAngewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee   +7 more
wiley   +2 more sources

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

open access: yesAdvanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu   +13 more
wiley   +1 more source

Urinary Sodium Loss following Hypertonic Saline Administration Curtails its Superior Osmolar Effect in Comparison to Mannitol in Severe Traumatic Brain Injury: A Secondary Analysis of a Randomized Controlled Trial

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2018
Background Mannitol and hypertonic saline (HTS) are used as boluses during episodes of raised intracranial pressure (ICP) in severe traumatic brain injury (TBI).
Aniruddha Tekkatte Jagannatha   +3 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

open access: yesAdvanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu   +8 more
wiley   +1 more source

Mannitol content in different parts of Fucus vesiculosus thallus from the Barents Sea in different seasons

open access: yesVestnik MGTU, 2018
The data on the mannitol content in different parts of the brown algae F. vesiculosus thallus from the Barents Sea have been obtained for the first time in different seasons.
Klindukh M. P.
doaj   +1 more source

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