Results 31 to 40 of about 127,314 (247)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Inducible Mtld expression facilitated the introduction of the mannitol synthesis pathway in Synechococcus elongatus PCC 7942

Frontiers in Bioengineering and Biotechnology
Mannitol is a valuable sugar alcohol, extensively used across various industries. Cyanobacteria show potential as future platforms for mannitol production, utilizing CO2 and solar energy directly. The proof-of-concept has been demonstrated by introducing
Jiahui Sun, Jiahui Sun, Jiahui Sun, Jiahui Sun, Jinyu Cui, Jinyu Cui, Jinyu Cui, Jinyu Cui, Xuejing Xu, Xuejing Xu, Xuejing Xu, Xuejing Xu, Jinhui Tang, Jinhui Tang, Jinhui Tang, Jinhui Tang, Huili Sun, Huili Sun, Huili Sun, Huili Sun, Xiangxiao Liu, Xiangxiao Liu, Xiangxiao Liu, Xiangyi Yuan, Xiangyi Yuan, Xiangyi Yuan, Guodong Luan, Guodong Luan, Guodong Luan, Guodong Luan, Guodong Luan, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu   +36 more
doaj   +1 more source

Effect of mannitol on cerebrovascular pressure reactivity in patients with intracranial hypertension

Journal of the Formosan Medical Association, 2015
Mannitol is commonly used in patients with increased intracranial pressure (ICP), but its effect on cerebrovascular pressure reactivity (CVPR) is uncertain.
Sung-Chun Tang, Ru-Jen Lin, Jiann-Shing Shieh, An-Yeu Wu, Dar-Ming Lai, Sheng-Jean Huang, Jiann-Shing Jeng   +6 more
doaj   +1 more source

Creation of combined stabilizing compositions to preserve the activity of gonadotropins in liquid form

Біологія тварин, 2022
The activity of dissolved enzyme preparations during storage decreases, what leads to the loss of their biological activity and, as a result, reduces the effectiveness of the drugs.
O. V. Shtapenko, I. I. Gevkan, V. Y. Syrvatka, O. Y. Slyvchuk, O. O. Korbetska, S. B. Kornyat, I. M. Yaremchuk   +6 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Comparison of Intestinal Permeability Methods in Broilers over a 6-Week Growth Period

Poultry, 2023
The adoption of methods detecting intestinal permeability in poultry has been slow due to the lack of urine availability in avian species. The objective of this study was to examine intestinal permeability assays in broilers using serum.
Maddison L. Wiersema, Brian J. Kerr, Dawn A. Koltes   +2 more
doaj   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Urinary Sodium Loss following Hypertonic Saline Administration Curtails its Superior Osmolar Effect in Comparison to Mannitol in Severe Traumatic Brain Injury: A Secondary Analysis of a Randomized Controlled Trial

Journal of Neuroanaesthesiology and Critical Care, 2018
Background Mannitol and hypertonic saline (HTS) are used as boluses during episodes of raised intracranial pressure (ICP) in severe traumatic brain injury (TBI).
Aniruddha Tekkatte Jagannatha, Kamath Sriganesh, Bhagavatula Indira Devi, Ganne Sesha Umamaheswara Rao   +3 more
doaj   +1 more source

Multiple Techno-Functional Characteristics of Leuconostoc and Their Potential in Sourdough Fermentations

Microorganisms, 2021
In this study, the potential of Leuconostoc as non-conventional sourdough starter cultures was investigated. A screening for antifungal activities of 99 lactic acid bacteria (LAB) strains revealed high suppression of bakery-relevant moulds in nine ...
Denise C. Müller, Sandra Mischler, Regine Schönlechner, Susanne Miescher Schwenninger   +3 more
doaj   +1 more source