Results 41 to 50 of about 152,345 (256)

Improved Enzymatic Method for Determining Mannitol and its Application to Dog Serum after Mannitol Infusion [PDF]

, 1980
Summary: An enzymatic method for mannitol quantitation has been developed. Its application in determining man-nitol levels in serum samples from dogs after mannitol infusion is illustrated. The method is based on the spectrophotometric measurement of the
Blomquist, C. H., B. D. Snyder, Snyder, B. D., Niehaus, W. G., W. G. Niehaus, C H. Blomquist   +5 more
core   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Inducible Mtld expression facilitated the introduction of the mannitol synthesis pathway in Synechococcus elongatus PCC 7942

Frontiers in Bioengineering and Biotechnology
Mannitol is a valuable sugar alcohol, extensively used across various industries. Cyanobacteria show potential as future platforms for mannitol production, utilizing CO2 and solar energy directly. The proof-of-concept has been demonstrated by introducing
Jiahui Sun, Jiahui Sun, Jiahui Sun, Jiahui Sun, Jinyu Cui, Jinyu Cui, Jinyu Cui, Jinyu Cui, Xuejing Xu, Xuejing Xu, Xuejing Xu, Xuejing Xu, Jinhui Tang, Jinhui Tang, Jinhui Tang, Jinhui Tang, Huili Sun, Huili Sun, Huili Sun, Huili Sun, Xiangxiao Liu, Xiangxiao Liu, Xiangxiao Liu, Xiangyi Yuan, Xiangyi Yuan, Xiangyi Yuan, Guodong Luan, Guodong Luan, Guodong Luan, Guodong Luan, Guodong Luan, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu, Xuefeng Lu   +36 more
doaj   +1 more source

Effect of mannitol on cerebrovascular pressure reactivity in patients with intracranial hypertension

Journal of the Formosan Medical Association, 2015
Mannitol is commonly used in patients with increased intracranial pressure (ICP), but its effect on cerebrovascular pressure reactivity (CVPR) is uncertain.
Sung-Chun Tang, Ru-Jen Lin, Jiann-Shing Shieh, An-Yeu Wu, Dar-Ming Lai, Sheng-Jean Huang, Jiann-Shing Jeng   +6 more
doaj   +1 more source

Inhaled mannitol for cystic fibrosis [PDF]

, 2018
Background: Several agents are used to clear secretions from the airways of people with cystic fibrosis. Mannitol increases mucociliary clearance, but its exact mechanism of action is unknown. The dry powder formulation of mannitol may be more convenient
Judith Thornton, Tiffany Dwyer, Sarah J Nevitt, Nevitt, SJ, Clare S Murray, Murray, CS, Thornton, J, Dwyer, T   +7 more
core   +1 more source

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz, Vít Herynek, Mária Hovořáková, Zuzana Pavlíková, Linda Dalecká, Klára Steklíková, Petr Matouš, Petr Páral, Margarita Tkachenko, Filip Koucký, Fatma Nalan Cetin, Ludmila Maffei Svobodová, Jiří Beneš, Kristýna Kolouchová   +13 more
wiley   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Production of pyruvate from mannitol by mannitol-assimilating pyruvate decarboxylase-negative Saccharomyces cerevisiae. [PDF]

, 2015
Mannitol is contained in brown macroalgae up to 33% (w/w, dry weight), and thus is a promising carbon source for white biotechnology. However, Saccharomyces cerevisiae, a key cell factory, is generally regarded to be unable to assimilate mannitol for ...
Murata, Kousaku, Kawai, Shigeyuki, Hirayama, Makoto, Yoshida, Shiori, Tanaka, Hideki   +4 more
core   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

Angewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee, Jung Min Kim, Joseph Blecha, Robert R. Flavell, Michael A. Ohliger, Joanne Engel, Youngho Seo, David M. Wilson   +7 more
wiley   +2 more sources