Poly(triazolyl methacrylate) glycopolymers as potential targeted unimolecular nanocarriers [PDF]
, 2019 © The Royal Society of Chemistry 2019.Synthetic glycopolymers are increasingly investigated as multivalent ligands for a range of biological and biomedical applications.
Fernandez-Trillo, F. +12 more
core +4 more sources
Recombinant Mannose-binding Lectin Protein and Anti-Mannose-binding Lectin Polyclonal Antibody Production [PDF]
Journal of Life Science, 2009 The innate immune system is important for the first line of host defence against infectious agents, which have penetrated the mechanical barriers. Mannose-binding lectin (MBL or mannan-binding protein, MBP) is a serum protein that is synthesized in the liver as a part of the acute phase response. MBL binds to carbohydrate structures presented by a wide
Hyun-Mi Kwon +4 more
openaire +2 more sources
Interaction of Diocleinae Lectins with Glycoproteins Based in Surface Plasmon Resonance
Memorias do Instituto Oswaldo Cruz, 2002 Interaction of glucose/mannose-binding lectins in solution with immobilized glycoproteins was followed in real time using surface plasmon resonance technology.
Marcio V Ramos +3 more
doaj +1 more source
Glyco-biomarkers: Potential determinants of cellular physiology and pathology [PDF]
, 2008 Once dismissed as just the icing on the cake, sugar molecules are emerging as vital components in life’s intricate machinery. Our understanding of their function within the context of the proteins and lipids to which they are attached has matured rapidly,
Alavi, A, Axford, JS
core +2 more sources
Isolation and partial characterisation of a novel lectin from Aegle marmelos fruit and its effect on adherence and invasion of Shigellae to HT29 cells. [PDF]
PLoS ONE, 2011 Lectins are a class of ubiquitous proteins/glycoproteins that are abundantly found in nature. Lectins have unique carbohydrate binding property and hence have been exploited as drugs against various infectious diseases.
Subramaniya Bharathi Raja +3 more
doaj +1 more source
The role of mannose-binding lectin in pneumococcal infection [PDF]
European Respiratory Journal, 2012 The role of mannose-binding lectin (MBL) deficiency (MBL2;XA/OandO/Ogenotypes) in host defences remains controversial. The surfactant proteins (SP)-A1, -A2 and -D, other collectins whose genes are located nearMBL2, are part of the first-line lung defence against infection.
Miguel A. García-Bello +15 more
openaire +4 more sources
Structural determinants for activity and specificity of the bacterial toxin LlpA. [PDF]
PLoS Pathogens, 2013 Lectin-like bacteriotoxic proteins, identified in several plant-associated bacteria, are able to selectively kill closely related species, including several phytopathogens, such as Pseudomonas syringae and Xanthomonas species, but so far their mode of ...
Maarten G K Ghequire +5 more
doaj +1 more source
Mannose‐Binding Lectin Polymorphisms in Clinical Tuberculosis [PDF]
The Journal of Infectious Diseases, 2003 Mannose-binding lectin (MBL) mediates protection against infections by using the complement system, but certain microorganisms may increase infectivity by exploiting this host defense system. Thus, it has been speculated whether genetically determined low MBL levels may confer partial protection against certain intracellular microorganisms, such as ...
Søborg, Christian +5 more
openaire +4 more sources
Mannose-Binding Lectin and Liver Transplantation [PDF]
Gastroenterology, 2005 Daniel L. Worthley +4 more
openalex +3 more sources
Retrospective screening of serum IgG glycosylation biomarker for primary Sjögren’s syndrome using lectin microarray [PDF]
PeerJ, 2023 Background Primary Sjögren’s syndrome (PSS) is a systemic autoimmune disease resulting in significant loss of systemic gland secretory function. IgG glycosylation abnormalities had been found to play important roles in autoimmune diseases.
Siting Li +7 more
doaj +2 more sources