Results 51 to 60 of about 25,372 (246)

A Keratin Peptide Inhibits Mannose-Binding Lectin [PDF]

The Journal of Immunology, 2001
Abstract Complement plays a significant role in mediating endothelial injury following oxidative stress. We have previously demonstrated that the lectin complement pathway (LCP), which is initiated by deposition of the mannose-binding lectin (MBL), is largely responsible for activating complement on endothelial cells following periods of
M C, Montalto, C D, Collard, J A, Buras, W R, Reenstra, R, McClaine, D R, Gies, R P, Rother, G L, Stahl   +7 more
openaire   +2 more sources

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation. [PDF]

, 1983
We are investigating the hypothesis that carbohydrate-binding molecules on the cell surface are involved in the recirculation of lymphocytes from the bloodstream into lymphoid organs.
Rosen, SD, Stoolman, LM
core   +1 more source

Mannose-Binding Lectin and Susceptibility to Schistosomiasis [PDF]

The Journal of Infectious Diseases, 2013
Human ficolin 2 (encoded by FCN2) and mannose-binding lectin (encoded by MBL2) bind to specific pathogen-associated molecular patterns, activate the complement lectin cascade in a similar manner, and are associated with several infectious diseases. Our recently published study established certain FCN2 promoter variants and ficolin-2 serum levels as ...
Justin S, Antony, Olusola, Ojurongbe, Hoang, van Tong, Eman Abou, Ouf, Thomas, Engleitner, Akeem A, Akindele, Olawumi R, Sina-Agbaje, Adegboyega O, Adeyeba, Peter G, Kremsner, Thirumalaisamy P, Velavan   +9 more
openaire   +3 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]

, 2009
We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Altschuler Y., Gabius H.J., Gendler S., Gouyer V., Hennebicq-Reig S., Huang J., Ligtenberg M.J., Ninomiya H., Yamashita K.   +8 more
core   +3 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Bacterial surface display of human lectins in Escherichia coli

Microbial Biotechnology
Lectin‐glycan interactions sustain fundamental biological processes involved in development and disease. Owing to their unique sugar‐binding properties, lectins have great potential in glycobiology and biomedicine.
Alba Vázquez‐Arias, Lorena Vázquez‐Iglesias, Ignacio Pérez‐Juste, Jorge Pérez‐Juste, Isabel Pastoriza‐Santos, Gustavo Bodelon   +5 more
doaj   +1 more source

Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles [PDF]

, 2015
The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca.
Allen, Arap, Bechet, Bertrand, Boya, Bullous, David A. Russell, Davis, Dougherty, Gary-Bobo, Girgis Obaid, Hamblin, Harris, Hogemann-Savellano, Hone, Isabelle Chambrier, Iversen, Jeyaprakash, Jin, Kim, Konska, Kopeček, Lindig, Marín, Mew, Michael J. Cook, Obaid, Oleinick, Orlova, Poiroux, Qualls, Robertson, Ross, Schafer, Schrama, Slamon, Spring, Springer, Stuchinskaya, Sudimack, Tang, Vacha, Wang, Weissenbock, Wieder, Xu, Yarden, Yu, Yu, Zhang   +49 more
core   +1 more source

OsEUL lectin gene expression in rice : stress regulation, subcellular localization and tissue specificity [PDF]

, 2020
The Euonymus lectin (EUL) family is a unique group of carbohydrate-binding proteins that is omnipresent in plants. Sequences encoding EUL-related lectins have been retrieved from all completely sequenced plant genomes.
De Zaeytijd, Jeroen, Demirel Asci, Sinem, Dubiel, Malgorzata, Lambin, Jeroen, Smagghe, Guy, Subramanyam, Kondeti, Tsaneva, Mariya Tsankova, Van Damme, Els, Verbeke, Isabel, Wytynck, Pieter   +9 more
core   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source