Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction [PDF]
Since the largest 2014-2016 Ebola virus disease outbreak in West Africa, understanding of Ebola virus infection has improved, notably the involvement of innate immune mediators. Amongst them, collectins are important players in the antiviral innate immune defense.
arxiv +1 more source
Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles. [PDF]
Hepatic sinusoidal endothelial cells are unique among endothelial cells in their ability to internalize and process a diverse range of antigens. DC-SIGNR, a type 2 C-type lectin expressed on liver sinusoids, has been shown to bind with high affinity to ...
Adam Jennings+61 more
core +2 more sources
Differential effect of plant lectins on mast cells of different origins
Histamine release induced by plant lectins was studied with emphasis on the carbohydrate specificity, external calcium requirement, metal binding sites, and mast cell heterogeneity and on the importance of antibodies bound to the mast cell membrane to ...
F.C. Lopes+4 more
doaj +1 more source
Lectins Are the Sparkle of Hope for Combating Coronaviruses and the Global COVID-19 [PDF]
Today the crisis of coronavirus disease 2019 (COVID-19) pandemic represents a threatworldwide because it is a leading cause of human morbidity and mortality. Besides, it possessesa destroying impact on countries’ economies.
Heba Salah Abbas+1 more
doaj +1 more source
High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300 [PDF]
To characterize the interaction potential of the human vaginal isolate Lactobacillus plantarum CMPG5300, its genome was mined for genes encoding lectin-like proteins.
Balzarini, Jan+10 more
core +1 more source
From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism [PDF]
Dendritic cells are known to be activated by a wide range of microbial products, leading to cytokine production and increased levels of membrane markers such as major histocompatibility complex class II molecules. Such activated dendritic cells possess the capacity to activate na\"ive T cells.
arxiv +1 more source
Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B+3 more
core +2 more sources
Lectin cDNA clones for two different lectins from garlic (Allium sativum L.) bulbs, ASAI and ASAII (ASA, Allium sativum agglutinin), were isolated and characterized.
E. J. M. Damme+5 more
semanticscholar +1 more source
Lectins and adhesins are involved in bacterial adhesion to host tissues and mucus during early steps of infection. We report the characterization of BC2L-C, a soluble lectin from the opportunistic pathogen Burkholderia cenocepacia, which has two distinct
Ondřej Sulák+13 more
doaj +1 more source
The Mannose-Binding Lectin: An Infection Susceptibility Gene [PDF]
A critical but unanswered question is what defines each individual’s pre-morbid susceptibility to infection? w e propose that individuals must have an “immune haplotype” that shapes their response to infectious agents. Infection is a balance between the intrinsic virulence of the infectious agent and the host defenses.
Lei Shi+3 more
openaire +3 more sources