Results 81 to 90 of about 26,256 (286)
The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova+1 more
doaj +1 more source
New challenges in studying nutrition-disease interactions in the developing world. [PDF]
Latest estimates indicate that nutritional deficiencies account for 3 million child deaths each year in less-developed countries. Targeted nutritional interventions could therefore save millions of lives.
Abdeljaber+24 more
core +3 more sources
A novel family of water‐soluble, nontoxic, and phosphorescent N‐glycosylated Ru(II) phenanthroline‐based complexes are reported. They exhibit photoselectivity indexes ranging from 10 to 44 in PC‐3 cells, while impacting cell migration and resistance to detachment after irradiation with blue light.
Elena de la Torre‐Rubio+5 more
wiley +1 more source
Lectins from the Edible Mushroom Agaricus bisporus and Their Therapeutic Potentials
The mushroom Agaricus bisporus secretes biologically active compounds and proteins with benefits for human health. Most reported proteins from A. bisporus are tyrosinases and lectins. Lectins are of therapeutic or pharmaceutical interest.
Wangsa Tirta Ismaya+2 more
doaj +1 more source
Acanthamoeba Mannose and Laminin Binding Proteins Variation across Species and Genotypes
Acanthamoeba is a ubiquitous free-living amoeba capable of being an opportunistic pathogen in humans and animals. A critical step in infection is the adhesion of the amoeba to host cells and tissues, and two major parasite adhesins, mannose-binding ...
Daniele Corsaro
doaj +1 more source
The stereochemical diversity of the “glycan code” enables similar chiral motifs to arise from both D‐ and L‐sugars. Focused on DC‐SIGN–glycan recognition, two diverse monosaccharide scaffolds, D‐Man (D‐Rha) and L‐Gal (L‐Fuc), maintain the exquisite stereochemistry encoded in the minimal binding epitope.
J. Daniel Martínez+7 more
wiley +1 more source
Molecular recognition of surface-immobilized carbohydrates by a synthetic lectin
The molecular recognition of carbohydrates and proteins mediates a wide range of physiological processes and the development of synthetic carbohydrate receptors (“synthetic lectins”) constitutes a key advance in biomedical technology.
Melanie Rauschenberg+4 more
doaj +1 more source
Structural basis for disparate sugar-binding specificities in the homologous cargo receptors ERGIC-53 and VIP36. [PDF]
ERGIC-53 and VIP36 are categorized as leguminous type (L-type) lectins, and they function as cargo receptors for trafficking certain N-linked glycoproteins in the secretory pathway in animal cells. They share structural similarities in their carbohydrate
Tadashi Satoh+3 more
doaj +1 more source
Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins
The synthesis of triterpenoid saponins bearing a Lewis‐X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin‐targeted therapeutic applications, are prepared through iterative and ...
Oscar Javier Gamboa Marin+3 more
wiley +1 more source
Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation. [PDF]
We are investigating the hypothesis that carbohydrate-binding molecules on the cell surface are involved in the recirculation of lymphocytes from the bloodstream into lymphoid organs.
Rosen, SD, Stoolman, LM
core +1 more source