Results 131 to 140 of about 171,360 (247)

Multimodal evaluation of mannose engineered poly lactic glycolic acid nanoparticles with granulocyte colony stimulating factor focused delivery to bone marrow for neutropenia. [PDF]

Sci Rep
Karwasra R, Bano N, Ahmad S, Singh S, Khanna K, Sharma N, Raza K, Verma S.   +7 more
europepmc   +1 more source

Glucosamine induces apoptosis of cholangiocarcinoma cells by suppressing high-mannose type <i>N</i>-glycosylation and EGFR/STAT3 signaling. [PDF]

Future Sci OA
Waenphimai O, Taebprakhon C, Phoomak C, Chu C, Silsirivanit A, Wongkham S, Saengboonmee C.   +6 more
europepmc   +1 more source

Plasmonic Heterojunction Nanomaterials for Noninvasive Pan‐Cancer Metabolomic Screening

Interdisciplinary Materials, EarlyView.
This study develops gold nanoparticle‐modified manganese–cobalt oxide heterjunctions (Au/MCOM) as a laser desorption/ionization mass spectrometry (LDI‐MS) matrix for acquiring serum metabolic fingerprints. Combined with machine learning, the platform achieves accurate detection and early screening across six cancer types, demonstrating strong potential
Jia Qi, Hairu Lin, Caiyun Fang, Jia Li, Fangying Shi, Chunhui Deng   +5 more
wiley   +1 more source

Fluorinated Glycan Frameshifts: Automated Synthesis Expedites the Study of Glycan-Protein Interactions by ¹⁹F-BioNMR. [PDF]

Angew Chem Int Ed Engl
Suri J, Jordan C, Teschers CS, Schlangen K, Rüdisser SH, Gossert AD, Gilmour R.   +6 more
europepmc   +1 more source

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source

Effects of Different Types of Lactobacillus helveticus Exopolysaccharides on Immune Function in Immunodeficient Mice. [PDF]

Foods
Wang S, Wang H, Li F, Zhao Y, Pei Z, Lu W, Zhao J, Lu S.   +7 more
europepmc   +1 more source

Host‐driven hepatic conversion of gut microbiota‐derived putrescine to spermidine mediates mannose's protective effects against hepatic steatosis in zebrafish

iMeta, EarlyView.
Evidence for liver metabolism of gut‐derived microbial compounds into beneficial secondary metabolites has been lacking. Here, we demonstrate that Cetobacterium somerae (C. somerae), enriched by mannose supplementation under high‐fat diet conditions, convert arginine into putrescine.
Delong Meng, Zhen Zhang, Tsegay Teame, Benjamin Earl Niemann, Rui Xia, Shichang Xu, Yajie Zhao, Yalin Yang, Chao Ran, Le Luo Guan, Zhigang Zhou   +10 more
wiley   +1 more source

Quantitative and Comparative Assessment of Recombinant Human β-Glucocerebrosidase Uptake Bioactivity Using a Stable hMMR-Expressing CHO Cell Model. [PDF]

Molecules
Wang L, Xu K, Lyu P, Hu X, Li J.
europepmc   +1 more source

The role of the gut microbiome in the regulation of high‐altitude adaptation

iMeta, EarlyView.
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang, Senlin Zhu, Michael Kreuzer, Shoukun Ji, Wei Wang, Yanliang Bi, Shengli Li   +6 more
wiley   +1 more source

Steroid-Refractory Cryptogenic Organising Pneumonia (COP) in a Patient With Mannose-Binding Lectin (MBL) Deficiency. [PDF]

Respirol Case Rep
Dimeas IE, Sinis SI, Kirgou P, McCarthy C, Daniil Z.   +4 more
europepmc   +1 more source