Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, EarlyView.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
Depression of Guanosine Diphosphate-Mannose Pyrophosphorylase by Mutations in Two Different Regulator Genes Involved in Capsular Polysaccharide Synthesis in Escherichia coli K-12 [PDF]
, 1970 Michael M. Lieberman, Alvin Markovitz
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Reactivity of Carbohydrate Phosphodiesters, Potential Targets of Antibacterial Agents
Chemistry &Biodiversity, EarlyView.A simple carbohydrate phosphodiester model was synthesized to compare the reactivity of phosphodiester bonds within carbohydrates and RNA. ABSTRACT While monosaccharide units in bacterial carbohydrates may be linked with phosphodiester bonds, human carbohydrates exclusively contain glycosidic linkages.
Eero Sillanpää +2 more
wiley +1 more source
Gargoylism: hydrolysis of β-galactosides and tissue accumulation of galactose- and mannose-containing compounds [PDF]
, 1970 Björn Hultberg +2 more
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ChemistryEurope, EarlyView.A borrowing hydrogen strategy using an NHC‐Ir(III) catalyst enables selective N‐functionalization of unprotected amino sugars using alcohols as alkylating agents. The use of unprotected substrates avoids extra steps of protection/deprotection, minimizing waste generation.
Aitor Bermejo‐López +7 more
wiley +1 more source
Design of a nanostructured lipid carrier intended to improve the treatment of tuberculosis
Drug Design, Development and Therapy, 2016 Marina Pinheiro,1,* Ricardo Ribeiro,1,* Alexandre Vieira,1,* Fernanda Andrade,2 Salette Reis1 1IUCIBIO, REQUIMTE, Chemistry Department, Faculty of Pharmacy, 2Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy ...
Pinheiro M +4 more
doaj
Aminosugars. XX. Synthesis of Some Derivatives of 2-Acetamido-2-deoxy-D-mannose [PDF]
, 1972 Juji Yoshimura +3 more
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Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
ChemistryEurope, EarlyView.Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source
Phosphoglucomutase Kinetics with the Phosphates of Fructose, Glucose, Mannose, Ribose, and Galactose
, 1969 O. H. Lowry, Janet V. Passonneau
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ChemistryEurope, EarlyView.This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink +3 more
wiley +1 more source