We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh +8 more
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Mannose metabolic pathway senses glucose supply and regulates cell fate decisions. [PDF]
Wang Z +8 more
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Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki +5 more
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Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity. [PDF]
Lindelöf L +13 more
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Due to a broad spectrum of active ingredients, snail slime presents a variety of exciting physical properties and chemical reactivities. Especially in the role of the reduction‐ and stabilizing agent for the manufacturing of gold nanoparticles, its great potential is revealed. Utilising the proteins found in slime, Nanoparticle‐comprising hydrogels are
Andrea Koball, Jens Gaitzsch
wiley +1 more source
Collateral Impact of Mannose Supplementation on Metastatic Properties in Osteosarcoma Cell Models. [PDF]
Morita A, Hara T.
europepmc +1 more source
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Altering the carbohydrate-binding specificity of the legume lectin FRIL through structure-guided engineering. [PDF]
Liu YM +9 more
europepmc +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Enhanced spinosad production in <i>Saccharopolyspora spinosa</i> by employing mannose as an extracellular carbon reservoir and optimizing acetyl-CoA supply pathway. [PDF]
Zhu Z +12 more
europepmc +1 more source

