Results 51 to 60 of about 102,260 (189)

Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers

Advanced Healthcare Materials, EarlyView.
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao, Zheng Zhang, Xincai Wu, Yanwei Chen, Wenjun Li, Jiayan Bao, Xin Zhang, Baoding Chen   +7 more
wiley   +1 more source

Ionic Conductive Textiles for Wearable Technology

Advanced Materials, EarlyView.
Recent advances in ionic conductive textiles for wearable technology are summarized, with a focus on soft ionic conductors that exhibit skin‐like flexibility and tissue‐like ion dynamics. Their structures, key characteristics, manufacturing methods, and diverse applications are reviewed.
Lingtao Fang, Yunlu Zhou, Qiyao Huang
wiley   +1 more source

Unveiling the metabolic fate of monosaccharides in cell membranes with glycomic and glycoproteomic analyses. [PDF]

, 2019
Cell membrane protein glycosylation is dependent on the metabolic state of the cell as well as exogenous nutrients available. Although the metabolism and interconversion of monosaccharides have been well-studied, their incorporation into cell surface ...
Cheng, Zhi, Lebrilla, Carlito B, Li, Qiongyu, Park, Dayoung, Wong, Maurice, Xu, Gege   +5 more
core  

Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration. [PDF]

, 2018
Kifunensine, a potent and selective inhibitor of class I α-mannosidases, prevents α-mannosidases I from trimming mannose residues on glycoproteins, thus resulting in oligomannose-type glycans.
Kailemia, Muchena J, Lebrilla, Carlito B, Li, Qiongyu, McDonald, Karen A, Nandi, Somen, Xiong, Yongao   +5 more
core   +3 more sources

Effects of .ALPHA.-D-mannose and equilibrated D-mannose on insulin release.

Endocrinologia Japonica, 1978
The effects on insulin release of alpha-D-mannose and equilibrated D-mannose were studied in the isolated perfused rat pancreas. Although phosphomannose isomerase, in contrast to phosphoglucose isomerase, is stereospecific for beta-D-mannose-6-phosphate, the alpha anomer of D-mannose (2 mg/ml) was significantly more effective than equilibrated D ...
Ichitomo Miwa, Hatsumi Niki, Atsushi Niki   +2 more
openaire   +4 more sources

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

Advanced Materials Interfaces, EarlyView.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu   +7 more
wiley   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source

Lectin-like bacteriocins from pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor [PDF]

, 2014
Lectin-like bacteriocins consist of tandem monocot mannose-binding domains and display a genus-specific killing activity. Here we show that pyocin L1, a novel member of this family from Pseudomonas aeruginosa, targets susceptible strains of this species ...
A Hviid, A Molinaro, AC Graham, AD Vinion-Dubiel, AHA Parret, AHA Parret, AJ McCoy, Aleksander W. Roszak, AM Abdel-Mawgoud, AW Schuttelkopf, Brian Smith, C Kleanthous, C Manichanh, CL Brown, CL Ng, D Franke, D Walker, Daniel Walker, DI Svergun, E Cascales, E Kurimoto, EJM Van Damme, F Gorrec, F Long, G Gorkiewicz, G Hester, G Kurisu, GN Murshudov, GR Vasta, Guy Tran Van Nhieu, HL Rocchetta, Inokentijs Josts, J Henao-Mejia, J Qin, JAM Fyfe, JB Lyczak, Joel Milner, JS Lam, JU Scher, K Smith, K Zeth, Kai I. Waløen, KC Carroll, KH Caffall, L Holm, L Stewart, Laura C. McCaughey, M Ramm, M Rivera, M Shimokawa, M-F Incardona, MA Jacobs, MB Kozin, ME Spehlmann, MGK Ghequire, MGK Ghequire, MGK Ghequire, MJ Claesson, N Sharon, Nicholas P. Tucker, NR Chandra, Olwyn Byron, P Emsley, PD Adams, PV Konarev, R Grinter, R Grinter, RA Laskowski, Rhys Grinter, Richard J. Cogdell, S Mori, Sharon Kelly, SY Shaw, T Ogawa, Tom Evans, V Ovod, VB Chen, VV Ovod, VV Volkov, WF Vranken, Y Hao, Y Michel-Briand, YA Knirel   +82 more
core   +4 more sources

The ‘involution’ of mannose-binding lectin [PDF]

Human Molecular Genetics, 2005
Mannose-binding lectin (MBL) acts as a serum opsonin in innate immune defense and induces complement activation by the lectin pathway. In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.
Hans O. Madsen, Peter Garred, Jeanette Seyfarth   +2 more
openaire   +3 more sources

Microbiome Single Cell Atlases Generated with a Commercial Instrument

Advanced Science, EarlyView.
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li, Linfeng Xu, Benjamin Demaree, Cecilia Noecker, Jordan E. Bisanz, Daniel W. Weisgerber, Cyrus Modavi, Peter J. Turnbaugh, Adam R. Abate   +8 more
wiley   +1 more source