Results 51 to 60 of about 175,359 (294)

Mannose phosphorylation in health and disease

European Journal of Cell Biology, 2010
Lysosomal hydrolases catalyze the degradation of a variety of macromolecules including proteins, carbohydrates, nucleic acids and lipids. The biogenesis of lysosomes or lysosome-related organelles requires a continuous substitution of soluble acid hydrolases and lysosomal membrane proteins.
Kollmann, Katrin, Pohl, Sandra, Marschner, Katrin, Encarnacao, Marisa, Sakwa, Imme, Tiede, Stephan, Poorthuis, Ben J., Lübke, Torben, Müller-Loennies, Sven, Storch, Stephan, Braulke, Thomas   +10 more
openaire   +5 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Microwave-Assisted Extraction of Polysaccharides from Chlorella pyrenoidosa and Its Characterization

Indonesian Journal of Chemistry
This study explored an efficient method for extracting polysaccharides from Chlorella pyrenoidosa using microwave-assisted extraction (MAE) with water as the solvent, a technique consistent with green chemistry principles.
Margaretha Praba Aulia, Muhammad Mufti Azis, Rochmadi Rochmadi, Arief Budiman   +3 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Role of glucuronoxylomannan and steryl glucosides in protecting against cryptococcosis

mBio
The development of vaccines for fungal diseases, including cryptococcosis, is an emergent line of research and development. In previous studies, we showed that a Cryptococcus mutant lacking the SGL1 gene (∆sgl1) accumulates certain glycolipids called ...
Gabriel Soares Matos, Samyr M. Querobino, Veronica S. Brauer, Luna S. Joffe, Nivea Pereira de Sa, Caroline Mota Fernandes, Deveney DaSilva, Vanessa A. da Silva, Marinaldo Pacífico Cavalcanti Neto, Tyler Normile, Hengwei Zhu, Surita R. Bhatia, Li Tan, Parastoo Azadi, Christian Heiss, Tamara L. Doering, Maurizio Del Poeta   +16 more
doaj   +1 more source

Ueber Mannose IV [PDF]

Berichte der deutschen chemischen Gesellschaft, 1889
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Fischer, Emil, Hirschberger, Josef
openaire   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

Advanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin, Sean P. Doidge, Eiman Aleem, Suela Kellici, Steven Dunn, Claire Atkinson, Philip D. Howes   +6 more
wiley   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Mannose-Decorated Solid-Lipid Nanoparticles for Alveolar Macrophage Targeted Delivery of Rifampicin

Pharmaceutics
Alveolar macrophages play a vital role in a variety of lung diseases, including tuberculosis. Thus, alveolar macrophage targeted anti-tubercular drug delivery through nanocarriers could improve its therapeutic response against tuberculosis.
Hriday Bera, Caizhu Zhao, Xidong Tian, Dongmei Cun, Mingshi Yang   +4 more
doaj   +1 more source

Dynamics of α-D-mannose carbohydrate-binding sites distribution in rats’ pancreatic structures during the morpho-functional formation

Zaporožskij Medicinskij Žurnal, 2017
Recently, the pathology of pancreas in children is observed more frequently. Precursors of inflammation development in pancreas are dysfunctional disorders, which include conditions accompanied by changes in pancreatic secretion in the absence of ...
N. V. Hrinivetska, Yu. A. Burega, I. M. Maslova   +2 more
doaj   +1 more source