Results 61 to 70 of about 208,518 (201)

3,4,6-Tri-O-acetyl-1-S-acetyl-2-deoxy-2-S-phenylthio-α-d-mannopyranoside

Molbank
The title compound was isolated as the unexpected reaction product from a reaction attempting to access a glycosyl 1-phosphate. The product was isolated in good yield, as one diastereoisomer, and was characterised by 1H, 13C, and 2D NMR, alongside HRMS ...
Jack Porter, Gavin J. Miller
doaj   +1 more source

Microwave-Assisted Extraction of Polysaccharides from Chlorella pyrenoidosa and Its Characterization

Indonesian Journal of Chemistry
This study explored an efficient method for extracting polysaccharides from Chlorella pyrenoidosa using microwave-assisted extraction (MAE) with water as the solvent, a technique consistent with green chemistry principles.
Margaretha Praba Aulia, Muhammad Mufti Azis, Rochmadi Rochmadi, Arief Budiman   +3 more
doaj   +1 more source

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

, 2017
Background: Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors.
E. Soemirien Kasanmoentalib (7747040), Aeilko H. Zwinderman (7714640), Diederik van de Beek (116723), Michael W. Tanck (7747046), Frank Baas (23060), Mercedes Valls Seron (7747043), Matthijs C. Brouwer (7747052), Bart Ferwerda (113577), William J. Schwaeble (7747049), Arie van der Ende (14875)   +9 more
core   +6 more sources

Role of glucuronoxylomannan and steryl glucosides in protecting against cryptococcosis

mBio
The development of vaccines for fungal diseases, including cryptococcosis, is an emergent line of research and development. In previous studies, we showed that a Cryptococcus mutant lacking the SGL1 gene (∆sgl1) accumulates certain glycolipids called ...
Gabriel Soares Matos, Samyr M. Querobino, Veronica S. Brauer, Luna S. Joffe, Nivea Pereira de Sa, Caroline Mota Fernandes, Deveney DaSilva, Vanessa A. da Silva, Marinaldo Pacífico Cavalcanti Neto, Tyler Normile, Hengwei Zhu, Surita R. Bhatia, Li Tan, Parastoo Azadi, Christian Heiss, Tamara L. Doering, Maurizio Del Poeta   +16 more
doaj   +1 more source

New mannose derivatives: The tetrazole analogue of mannose-6-phosphate as angiogenesis inhibitor [PDF]

Bioorganic & Medicinal Chemistry Letters, 2016
Two novel compounds with mannose-derived structure, bearing a tetrazole (compound 3) and a sulfone group (compound 4) in terminal position, have been prepared from methyl α-d-mannopyranoside in reduced number of steps. The angiogenic activity of 3 and 4 has been screened using the chick chorioallantoic membrane (CAM) method.
Cătălina Ionescu, Simona Sippelli, Loïc Toupet, Véronique Barragan-Montero   +3 more
openaire   +3 more sources

Elevated Serum Mannose Levels as a Marker of Polycystic Ovary Syndrome

Frontiers in Endocrinology, 2019
Background: Recent reports have highlighted the role of monosaccharide biosynthesis in the pathogenesis of polycystic ovary syndrome (PCOS), suggesting that these processes may serve as a biomarker in PCOS.
Di Feng, Bei Shi, Fangfang Bi, Matthew Sagnelli, Xiaoli Sun, Jiao Jiao, Xiuxia Wang, Da Li   +7 more
doaj   +1 more source

Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism [PDF]

, 1989
The removal of neutrophils and their histotoxic contents from the inflamed site is a prerequisite for resolution of tissue injury, and a point at which factors critical to the pathogenesis of chronic inflammation may act.
Savill, John S, J S Savill, Henson, P M, P M Henson, C Haslett, Haslett, Christopher   +5 more
core   +1 more source

Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides

Beilstein Journal of Organic Chemistry, 2019
Muramyl dipeptide is the minimal structure of peptidoglycan with adjuvant properties. Replacement of the N-acetylmuramyl moiety and increase of lipophilicity are important approaches in the preparation of muramyl dipeptide analogues with improved ...
Rosana Ribić, Ranko Stojković, Lidija Milković, Mariastefania Antica, Marko Cigler, Srđanka Tomić   +5 more
doaj   +1 more source

Causal effects of human serum metabolites on occurrence and progress indicators of chronic kidney disease: a two-sample Mendelian randomization study

Frontiers in Nutrition
BackgroundChronic kidney disease (CKD) is often accompanied by alterations in the metabolic profile of the body, yet the causative role of these metabolic changes in the onset of CKD remains a subject of ongoing debate.
Yu Yin, Conghui Shan, Qianguang Han, Congcong Chen, Zijie Wang, Zhengkai Huang, Hao Chen, Li Sun, Shuang Fei, Jun Tao, Zhijian Han, Ruoyun Tan, Min Gu, Min Gu, Xiaobing Ju   +14 more
doaj   +1 more source

Enhancement of polysaccharides accumulation in Dendrobium officinale by exogenously applied methyl jasmonate

Biologia Plantarum, 2017
The accumulation of polysaccharides, activities of sucrose metabolism enzymes, and the expression of sucrose biosynthetic genes in Dendrobium officinale were significantly affected by exogenous methyl jasmonate (MeJA).
Z. Q. Yuan, J. Y. Zhang, T. Liu
doaj   +1 more source